A0AAD9FVA5 · A0AAD9FVA5_PAPLA
- Proteinalpha-1,2-Mannosidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids873 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 123 | Proton donor | |||
Active site | 279 | ||||
Active site | 375 | Proton donor | |||
Active site | 394 | ||||
Binding site | 478 | Ca2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum quality control compartment | |
Cellular Component | membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | endoplasmic reticulum mannose trimming | |
Biological Process | mannose trimming involved in glycoprotein ERAD pathway |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namealpha-1,2-Mannosidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Rhynchogastremaceae > Papiliotrema
Accessions
- Primary accessionA0AAD9FVA5
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5042228458 | 22-873 | alpha-1,2-Mannosidase | ||
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 712-772 | PA | |||
Region | 832-853 | Disordered | |||
Compositional bias | 839-853 | Basic and acidic residues | |||
Sequence similarities
Belongs to the glycosyl hydrolase 47 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length873
- Mass (Da)97,140
- Last updated2024-05-29 v1
- MD5 ChecksumE3698F2712E96F6400E52374604FD64B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 839-853 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAODAN010000001 EMBL· GenBank· DDBJ | KAK1926910.1 EMBL· GenBank· DDBJ | Genomic DNA |