A0AAD9FPU9 · A0AAD9FPU9_PAPLA
- ProteinUrease
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids832 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- urea + 2 H2O + H+ = hydrogencarbonate + 2 NH4+
Cofactor
Note: Binds 2 nickel ions per subunit.
Pathway
Nitrogen metabolism; urea degradation; CO2 and NH3 from urea (urease route): step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 399 | Ni2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 401 | Ni2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 482 | Ni2+ 1 (UniProtKB | ChEBI); via carbamate group | |||
Binding site | 482 | Ni2+ 2 (UniProtKB | ChEBI); via carbamate group | |||
Binding site | 484 | substrate | |||
Binding site | 511 | Ni2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 537 | Ni2+ 2 (UniProtKB | ChEBI) | |||
Active site | 585 | Proton donor | |||
Binding site | 625 | Ni2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | urease complex | |
Molecular Function | nickel cation binding | |
Molecular Function | urease activity | |
Biological Process | urea catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUrease
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Rhynchogastremaceae > Papiliotrema
Accessions
- Primary accessionA0AAD9FPU9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 482 | N6-carboxylysine | |||
Post-translational modification
Carbamylation allows a single lysine to coordinate two nickel ions.
Structure
Sequence
- Sequence statusComplete
- Length832
- Mass (Da)89,858
- Last updated2024-05-29 v1
- MD5 ChecksumA865DB1069797327473E05F8D6CA8AAA
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAODAN010000012 EMBL· GenBank· DDBJ | KAK1920967.1 EMBL· GenBank· DDBJ | Genomic DNA |