A0AAD6JPW1 · A0AAD6JPW1_9ROSI
- ProteinNeutral ceramidase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids744 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- an N-acylsphing-4-enine + H2O = a fatty acid + sphing-4-enine
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | ceramidase activity | |
Molecular Function | N-acylsphingosine amidohydrolase activity | |
Biological Process | ceramide catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNeutral ceramidase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Malpighiales > Salicaceae > Saliceae > Salix
Accessions
- Primary accessionA0AAD6JPW1
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 39-395 | Neutral/alkaline non-lysosomal ceramidase N-terminal | ||||
Sequence: YLIGLGSYDITGPAADVNMMGYANTEQIASGVHFRLRARSFIVAQPQGNRVVFVNLDACMASQLVTIKVIERLKARYGDLYTEKNVAISGIHTHAGPGGYLQYVVYIVTSLGFVRQSFDALVDGIEKCIIQAHENLHPGSIFVNKGEILNAGVNRSPSAYLNNPVEERSKYKYDVDKEMTLLKFVDAERGPVGSFNWFATHGTSMSRTNSLISGDNKGAAARFMEDWFQHSGVGNLYSDDGVADGIPRRISNIIPDSHDNHHKLLELAASFQSPPGRPAKKILSVARRVRGALRQADKPGFVSAFCQSNCGDVSPNVLGAFCIDTGLPCDFNHSTCGGKNELCYGRGPGYPDEFENF | ||||||
Domain | 580-743 | Neutral/alkaline non-lysosomal ceramidase C-terminal | ||||
Sequence: FKKLAAALTSGRSVEPGPQPPDLLNEQISLLTPVVMDATPPGVHFGDCSSDVHLNSTFKRGDTVTVVFWSACPRNDLMTEGTFSLVEILQGKESWFPAYDDDDFCLLFKWSRPSKLSTRSHATIEWRIPQSATPGVYRIRHFGAAKSLFGSIRHFTGSSSAFVV |
Sequence similarities
Belongs to the neutral ceramidase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length744
- Mass (Da)81,590
- Last updated2024-05-29 v1
- ChecksumD1CFDA4F1070D479
Keywords
- Technical term