A0AAD5VI52 · A0AAD5VI52_9AGAR
- ProteinDNA 3'-5' helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1067 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromosome | |
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | four-way junction helicase activity | |
Molecular Function | hydrolase activity | |
Molecular Function | nucleic acid binding | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | double-strand break repair via homologous recombination |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA 3'-5' helicase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Leucocoprinus
Accessions
- Primary accessionA0AAD5VI52
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-144 | Disordered | ||||
Sequence: MSVPRNNLAELLKRKEQNALGSPQVYTPPPRTRSGPKFKPAISTPSGPSTNILFRTSRFFRHQDSRQAKPSPILTTTSEPIVISDYSNPETPHPLKRNSSDPDVVPDPSPQAFKRPKRAVIASDKENRPPPKVTPSSSKETTPT | ||||||
Compositional bias | 43-58 | Polar residues | ||||
Sequence: STPSGPSTNILFRTSR | ||||||
Compositional bias | 68-95 | Polar residues | ||||
Sequence: AKPSPILTTTSEPIVISDYSNPETPHPL | ||||||
Compositional bias | 130-144 | Polar residues | ||||
Sequence: PPKVTPSSSKETTPT | ||||||
Region | 245-270 | Disordered | ||||
Sequence: QRDMTTVSPNSQPISTPTISTPSITN | ||||||
Domain | 395-571 | Helicase ATP-binding | ||||
Sequence: ISATLEGKDVFVLMPTGGGKSLCYQLPAVCTSGKTCGVTIVVSPLTALMEDQVSALTAKGVDAFFWSADSLQHEVSAKLFSGDKKPSLLYVTPEKLRASSSCRNLLERLYRQQQLARFAIDEAHCISTWGQDFRSAYQGLGQLRQDYPNVPIIALTATANERTRDDIVDQLRLRNPA | ||||||
Domain | 592-755 | Helicase C-terminal | ||||
Sequence: VLDSIVDFIQRKHPNSSGVIYCLSRRSCQNLAEQLQSKGLRAEYFHAGLDKDTKNRLLEEWKKDKFRIIVATIAFGMGIDKPDVRFVIHHDLPKSLSGYYQETGRAGRDGKPADCVLYYSYKDFLTICWMIENDTEREEPLTPEGIDRQKNAAREVVKYCNNIS | ||||||
Region | 895-966 | Disordered | ||||
Sequence: LLVKWRPPPPKAAKAPKQNQERPGKGKGRAAGPVVADPIESFPDDETPKATGSSSTQSSSTPPQPTPFPDTM | ||||||
Compositional bias | 941-955 | Polar residues | ||||
Sequence: TPKATGSSSTQSSST |
Sequence similarities
Belongs to the helicase family. RecQ subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,067
- Mass (Da)119,214
- Last updated2024-05-29 v1
- Checksum67D1FF4BDA54E9A0
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 43-58 | Polar residues | ||||
Sequence: STPSGPSTNILFRTSR | ||||||
Compositional bias | 68-95 | Polar residues | ||||
Sequence: AKPSPILTTTSEPIVISDYSNPETPHPL | ||||||
Compositional bias | 130-144 | Polar residues | ||||
Sequence: PPKVTPSSSKETTPT | ||||||
Compositional bias | 941-955 | Polar residues | ||||
Sequence: TPKATGSSSTQSSST |
Keywords
- Technical term