A0AAD5VFI6 · A0AAD5VFI6_9AGAR

Function

function

ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G2/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionDNA binding
Molecular FunctionDNA helicase activity
Molecular Functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Molecular Functioniron-sulfur cluster binding
Molecular Functionisomerase activity
Molecular Functionmetal ion binding
Biological Processestablishment of sister chromatid cohesion
Biological Processnucleobase-containing compound metabolic process
Biological Processphosphorelay signal transduction system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase CHL1
  • EC number
  • Alternative names
    • ATP-dependent DNA helicase chl1
    • Chromosome loss protein 1
    • DNA 5'-3' helicase CHL1

Gene names

    • ORF names
      NP233_g11962

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • VT141
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Agaricineae > Agaricaceae > Leucocoprinus

Accessions

  • Primary accession
    A0AAD5VFI6

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue33Phosphohistidine

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain1-94HPt
Domain187-588Helicase ATP-binding
Region284-316Disordered
Compositional bias289-304Basic and acidic residues
Region387-407Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,028
  • Mass (Da)
    115,672
  • Last updated
    2024-05-29 v1
  • Checksum
    8F8E040B0BF70A9E
MVEGFYDQAEETFQSMDGYLESKNLSELSEKGHFLKGSSAAIGITKVQRSCEEIQNYGKLQGNDEKPISTAEALERLQKVLARVKGEYEEAKDWLNQCTIDSKSCTSDPYLHPFCLNTFPPSSICLPVLALFLLIISILRSFFSHSSHRQEPLMMMTSSLHVMLESNSRVRPSTRPASMDLHLQTPDGFPAFPYDLPYPIQTDLMRHLYENIENRAITIVESPTGTNSSLIFDQGKEWVIEQTRERIRRQLEADELAYQERLVSAGRREEAMRRAARARVLKKPKWGGKGLQEQARRKEEHQDEDDDIFLPDDDRGTQEDEVFISPALQALINRVDKPSRPGSDDAEEVTCTKVYYASRTHSQLAQVLPELRRLKLFRLSSITSDQLPHQQRSSVPHKRGLGNLEEGEETEIMTRTVPLGSRRQLCINEKLRSKAQDLDEACRELLSEKGDKRCPYLPPLDEDIKMIDFRDQILAVPKDIEDLAEAGRLAETCPYFGSRRAIPQAELVTLPYNLLLQKSAREALGIDLKDQIVVIDEAHNLIPTLLSLSTIRLPFNTLDTSLQQVCTYVSKFRTRLSATNMVHLKRLVVFLDALKKFLLQWKESRCTELLKAGGKIEKIDVLTVAELLERMGRKAAGINLLEVEGYLKKSKIARKISGYADKQSAKGIETPASRQVRKGQIPPLHIVEDLMIALTNTNDDGRVTLTLAGSRGQEEVEIKYQLLNPAPNFVEIADEARSVVLAGGTMSPMSDVVNQLFSHVPPERITTFSCGHIIPEENLQALVVTKSPRGHDVEFKADKQGDPEVVAELGQTLLNLINVVPAGVVVFFPSYNFLKSAKLVWEKSGTLEKLSVKREVFFEPDESIDVERVLSDYATAATSPPKSKKGAVLFAVIGAKLSEGLNFNDDLARAVIIIGLPFANLGSPELKERLKYVKQLEEKKGVKREKGQKDAAAELYENMCMNAVNQSIGRAIRHKGDWASLILLDRRYASSAIRKKLPKWIGSRLFVPEGFGQTMKQLGQFYREKKSS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias289-304Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JANIEX010001571
EMBL· GenBank· DDBJ
KAJ3556498.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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