A0AAD3S7A6 · A0AAD3S7A6_NEPGR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site102substrate 1; for methylthioribulose-1-phosphate dehydratase activity
Binding site120Zn2+ (UniProtKB | ChEBI)
Binding site122Zn2+ (UniProtKB | ChEBI)
Active site145Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity
Binding site195Zn2+ (UniProtKB | ChEBI)
Binding site277Mg2+ (UniProtKB | ChEBI)
Binding site279Mg2+ (UniProtKB | ChEBI)
Binding site412-413substrate 2; for enolase-phosphatase activity
Binding site446substrate 2; for enolase-phosphatase activity
Binding site472Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
Molecular Function2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
Molecular Functionacireductone synthase activity
Molecular Functionmagnesium ion binding
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1

Including 2 domains:

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase
  • Recommended name
    Enolase-phosphatase E1
  • EC number
  • Alternative names
    • 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Gene names

    • ORF names
      Nepgr_007474

Organism names

  • Taxonomic identifier
  • Strain
    • SING2019-196
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > Caryophyllales > Nepenthaceae > Nepenthes

Accessions

  • Primary accession
    A0AAD3S7A6

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-230Methylthioribulose-1-phosphate dehydratase
Domain19-222Class II aldolase/adducin N-terminal
Region274-513Enolase-phosphatase E1

Sequence similarities

In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    513
  • Mass (Da)
    57,153
  • Last updated
    2024-05-29 v1
  • Checksum
    26860FF60D89F8F8
MATTTQAYIESKPVQETKALITELCRQFYSQGWVGGTGGSITIKVHDDCIRKPQQLIIMSPSGVQKERMSPEDMYILSPDGTIISFPTPKPYPHKPPKCSDCAPIFMKAYQMRNAGAIIHSHGMESCLVTMINPGSKEFRITHMEMIKGIQGHGYYDELVVPIIENTAHERDLTNSLAGAIEAYPKSTAVLVRNHGIYVWGDSWISAKTQAECYHYLFDAAIKLYQLGLDWSTPTHGPIKAIKGVSKSGPHMTLSVKTGSKEFDRQMKALRRCIVLDIEGTATPISFVTDVLFPYACDNIGRHLRETYESAETRDDIELLRTQAQDDLEKGVAGAVPVPHLTERKEEVIAAVVANVEAMIKADRKITALKQLQGHIWRNGFQNKELEGVVFEDVPEALERWHASGIKVYIYSSGSRLAQRLLFGNTNFGDLRKYLSGYFDTTVGNKRESRSYMEIYESVGVDSPSELLFVTDVYEEAIAAKAAGLEVIISVRPGNGPLPKNHGFRMVNLFSEI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BSYO01000006
EMBL· GenBank· DDBJ
GMH05634.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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