A0AAD1NP79 · A0AAD1NP79_9GAMM

  • Protein
    Phosphoenolpyruvate-protein phosphotransferase
  • Gene
    ptsI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

156750100150200250300350400450500550
TypeIDPosition(s)Description
Active site188Tele-phosphohistidine intermediate
Binding site295phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site331phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site429Mg2+ (UniProtKB | ChEBI)
Binding site452-453phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site453Mg2+ (UniProtKB | ChEBI)
Binding site463phosphoenolpyruvate (UniProtKB | ChEBI)
Active site500Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsI
    • ORF names
      TUM17379_22900

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TUM17379
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Shewanellaceae > Shewanella

Accessions

  • Primary accession
    A0AAD1NP79

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-125Phosphotransferase system enzyme I N-terminal
Domain152-224PEP-utilising enzyme mobile
Domain252-536PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    567
  • Mass (Da)
    62,065
  • Last updated
    2024-05-29 v1
  • Checksum
    BD81E97DA4A43BA0
MRLAGIAVSSGIAFGEAVVYNPFDNSMDYRLLPLAKIPQELNKLTQALQRLCQQLQTSLDKLTEDSDNFQLVEADLLLLEDAELIQQIRESISGLQFSATAAVERVFAHQASELEALEDPYLANRAQDVRCLGRRLISSINGADADGLDKLKHDSILLAQDLTPAEFALLPLEHIKGIILKTGGLTSHTAILARAAGIPALLSCNYQTGNINAGDPLILDANQGALFVRPEQTEVTELKQRFEREQARRSALEQYRDRQTQTQDGKRISLMANVGNLNEISRLPQVGAEGIGLFRTEFMLTDVSCIPDEKAQYNLYCDALQLLNGQPFTIRTLDIGADKELPCLDQAIEDNPALGMRGVRYTLKHPEILQTQLRAVLRAANHGPVRLMLPMVNQVEELDAVLDMLEHCKQQLSEAEKGYGEITLGIVVETPAAVMNLPTLLPKLDFISIGTNDLTQYAMAADRTNPELTRDYPSFSPAILRLIAMTIADAKAADIRVSLCGELAGDPRIAPILMGMGLDELSVNPGSVLEVKAALCEGNFSQFADQAKKALACTRLSELTSLISLCH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024613
EMBL· GenBank· DDBJ
BCV45272.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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