A0AAD1BBW5 · A0AAD1BBW5_9PSED
- ProteinPeptide methionine sulfoxide reductase MsrA
- GenemsrA_2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids154 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Catalytic activity
- [thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:15377 + CHEBI:57844 = RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3+ CHEBI:58772
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 18 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | peptide-methionine (S)-S-oxide reductase activity | |
Biological Process | protein modification process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeptide methionine sulfoxide reductase MsrA
- EC number
- Short namesProtein-methionine-S-oxide reductase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0AAD1BBW5
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 11-153 | Peptide methionine sulphoxide reductase MsrA | ||||
Sequence: QATFGAGCFWGAEAAFRALPGVVDSRVGYAVEAADEALQIEVVQVDFDPQVLTYTSLIEHFWGLHDPTSVDRQGEHGGVKYRSAIFHTNAVQAEQARAAKTALQDSGRLNKPVATVIVPLGRFELADEAHQRYLEKNGLSSCH |
Sequence similarities
Belongs to the MsrA Met sulfoxide reductase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length154
- Mass (Da)16,666
- Last updated2024-05-29 v1
- Checksum7FDE7762C84F7A24