A0AAD1B7U8 · A0AAD1B7U8_9PSED
- ProteinPhenylalanine-4-hydroxylase
- GenephhA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids263 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine
Cofactor
Pathway
Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | iron ion binding | |
Molecular Function | phenylalanine 4-monooxygenase activity | |
Biological Process | L-phenylalanine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhenylalanine-4-hydroxylase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionA0AAD1B7U8
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-263 | Biopterin-dependent aromatic amino acid hydroxylase family profile | ||||
Sequence: MKQTQYVAREPDAQGFIDYPPEEHAVWNTLITRQLKVIEGRACQEYLDGIEKLGLPHDRIPQLSEINKVLGETTGWQVARVPALIPFQTFFELLASKRFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLTNPWFAEFTHTYGKLGLQATKEERVYLARLYWMTIEFGLVETPAGRRIYGGGILSSPKETVYSLSEAPEHQAFDPLEAMRTPYRIDILQPIYFVLPNLKRLFDLAHEDIMALVHQGMQLGLHAPKFPPKPKAA |
Sequence similarities
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length263
- Mass (Da)30,174
- Last updated2024-05-29 v1
- ChecksumA72A20961DC85E7C