A0AAD0KVK2 · A0AAD0KVK2_MYCLR

  • Protein
    Translation initiation factor IF-2
  • Gene
    infB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

1924100200300400500600700800900
TypeIDPosition(s)Description
Binding site429-436GTP (UniProtKB | ChEBI)
Binding site479-483GTP (UniProtKB | ChEBI)
Binding site533-536GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular Functiontranslation initiation factor activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Translation initiation factor IF-2

Gene names

    • Name
      infB
    • ORF names
      DIJ64_08540

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MRHRU-235-G
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium

Accessions

  • Primary accession
    A0AAD0KVK2

Proteomes

Subcellular Location

Keywords

Structure

3D structure databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region118-325Disordered
Compositional bias144-175Pro residues
Compositional bias191-205Pro residues
Domain420-591Tr-type G

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    924
  • Mass (Da)
    96,651
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    41779F5A0672D53204BF552A5B0D7B42
MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias144-175Pro residues
Compositional bias191-205Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP029543
EMBL· GenBank· DDBJ
AWV48091.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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