A0AAD0KVK2 · A0AAD0KVK2_MYCLR
- ProteinTranslation initiation factor IF-2
- GeneinfB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids924 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 429-436 | GTP (UniProtKB | ChEBI) | |||
Binding site | 479-483 | GTP (UniProtKB | ChEBI) | |||
Binding site | 533-536 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation initiation factor activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameTranslation initiation factor IF-2
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionA0AAD0KVK2
Proteomes
Subcellular Location
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 118-325 | Disordered | |||
Compositional bias | 144-175 | Pro residues | |||
Compositional bias | 191-205 | Pro residues | |||
Domain | 420-591 | Tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length924
- Mass (Da)96,651
- Last updated2024-05-29 v1
- MD5 Checksum41779F5A0672D53204BF552A5B0D7B42
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 144-175 | Pro residues | |||
Compositional bias | 191-205 | Pro residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP029543 EMBL· GenBank· DDBJ | AWV48091.1 EMBL· GenBank· DDBJ | Genomic DNA |