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A0AAD0EWM0 · A0AAD0EWM0_MOROS

  • Protein
    Histidine biosynthesis bifunctional protein HisIE
  • Gene
    hisI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.
Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionphosphoribosyl-AMP cyclohydrolase activity
Molecular Functionphosphoribosyl-ATP diphosphatase activity
Biological ProcessL-histidine biosynthetic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Histidine biosynthesis bifunctional protein HisIE

Including 2 domains:

  • Recommended name
    Phosphoribosyl-AMP cyclohydrolase
  • EC number
  • Short names
    PRA-CH
  • Recommended name
    Phosphoribosyl-ATP pyrophosphatase
  • EC number
  • Short names
    PRA-PH

Gene names

    • Name
      hisI
    • Synonyms
      hisIE
    • ORF names
      YHS_01130

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • YHS
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Moraxella

Accessions

  • Primary accession
    A0AAD0EWM0

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, domain, compositional bias.

Type
IDPosition(s)Description
Region1-168Phosphoribosyl-AMP cyclohydrolase
Domain29-103Phosphoribosyl-AMP cyclohydrolase
Region126-164Disordered
Compositional bias138-164Polar residues
Region169-285Phosphoribosyl-ATP pyrophosphohydrolase

Sequence similarities

In the C-terminal section; belongs to the PRA-PH family.
In the N-terminal section; belongs to the PRA-CH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    285
  • Mass (Da)
    31,695
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    C5F3AB60F893F6F163ABAE60C42C18EC
MDWLDTLKFDDNGLMPAVAQDFHTGRILMMAWMNRESLRLTAEKMQAVYWSRSRGKLWHKGESSGHFQQVHEIRLDCDADVIVLSVTQVGGIACHTGRQSCFYRLLADDRGQLQWQTTDAVIKDPDAIYGDNAKPTHEHSPLASNSTQISNPTQTSNATQTPTTSADILTALDEVLIGRKNANPDSSYVASLYHKGINKILEKVGEEATEAIIAAKDINIANDTPYEAVADDTAVKDLVYEIADVWFHTMVTLAWFNIPSWAVTNELARRFGLSGIDEKAARQIS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias138-164Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024176
EMBL· GenBank· DDBJ
ATQ82550.2
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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