A0AAD0APV2 · A0AAD0APV2_9FUSO

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

128020406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site12D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site69Schiff-base intermediate with D-ribose 5-phosphate
Binding site141D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site153D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site202D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site223-224D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processpyridoxal phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxS
  • EC number
  • Short names
    PLP synthase subunit PdxS
  • Alternative names
    • Pdx1

Gene names

    • Name
      pdxS
    • ORF names
      CTM74_13050
      , CTM86_00945

Organism names

  • Taxonomic identifier
  • Strains
    • KCOM 1263
    • KCOM 1282
  • Taxonomic lineage
    Bacteria > Fusobacteriota > Fusobacteriia > Fusobacteriales > Fusobacteriaceae > Fusobacterium

Accessions

  • Primary accession
    A0AAD0APV2

Proteomes

Interaction

Subunit

In the presence of PdxT, forms a dodecamer of heterodimers.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-200PdxS/SNZ N-terminal

Sequence similarities

Belongs to the PdxS/SNZ family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    280
  • Mass (Da)
    30,308
  • Last updated
    2024-05-29 v1
  • Checksum
    DD9729408395F7A3
MDTRFNGGVIMDVTSKEQAIIAEEAGAVAVMALERIPADIRAAGGVSRMSDPKLIKEIMSAVKIPVMAKVRIGHFVEAEILQAIGIDFIDESEVLSPADSVHHVNKRDFTTPFVCGARNLGEALRRICEGAQMIRTKGEAGTGDVVQAVSHMRQIMKEINLVKALRDDELYVMAKDLQVPYDLVKYVHDNGRLPVPNFSAGGVATPADAALMRRLGADGVFVGSGIFKSGDPRKRAKAIVEAVKNYDNPEIIARVSEDLGEAMVGINENEIKIIMAERGV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP024700
EMBL· GenBank· DDBJ
ATV62672.1
EMBL· GenBank· DDBJ
Genomic DNA
CP024702
EMBL· GenBank· DDBJ
ATV65258.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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