A0AAC9P8X6 · A0AAC9P8X6_9PROT

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site103Transition state stabilizer
Active site107Proton acceptor
Binding site268Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      GbCGDNIH9_1677

Organism names

  • Taxonomic identifier
  • Strain
    • NIH9.1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Granulibacter

Accessions

  • Primary accession
    A0AAC9P8X6

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain, cross-link.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_504175493526-741Catalase-peroxidase
Cross-link106↔227Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with Met-253)
Cross-link227↔253Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-106)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain140-415Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    741
  • Mass (Da)
    81,025
  • Last updated
    2024-05-29 v1
  • Checksum
    A777B18097D138E6
MHRTIRSVAAVLAAVLSATIPMAPAWSDGEPRSIQFWWPDHLDLSPLRQHAAESNPLGANFNYIKAFQTLDLDAVKKDIAVLLKTPQDWWPADYGNYGPFFIRMAWHGAGTYRTYDGRGGASGAQQRFEPLNSWPDNANLDKARRLLWPIKKKYGEKLSWGDLMVLTGNVALETMGFKTYGFAGGRTDDWEPDLIYWGAGAKFMSNNRDKNGKLEKPLAATQMGLIYVNPEGPNGVPDPLAAARDIREAFGGMAMDDEETVALIAGGHTFGKAHGAASPTKCVGPAPAAAGIEEQGLGWKNKCGTGKGPDTITSGLEGAWSADPVNFTSQYLDNLFGFDWVQTKSPGGAIQWKPKDASADQLVPDAFNASKRHPPMMFTTDIALKTDPAYRKIALSFQKDPEKFKAAFARAWFKLVHRDMGPRSRYFGPEVPKEDLLWQDPLPAITYKAVDESDIADLKQKILASGLAVPELVRTAWGSAASFRGTDKRGGANGARIRLAPEKDWPVNDPQELKKVLDKLESIQTAFNDGNHDGKKVSLADLIVLGGNVGIEEAAKKAGYPVVVPFTPGRADAVQAQTDVKSFAVLEPTADGFRNYYAASNQLSPAEMLVTRASMLDLTVPEMTVLVGGMRVLDANEGHSQLGVLTDHPGVLSNDFFVNLLDMSTKWSKAADTAGVYEGHDRKTNALRWKGSTVDLIFGSNSELRAVAEVYASDDAKEKFVHDFVAAWNKVMMLDRFDLQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP018191
EMBL· GenBank· DDBJ
APH54977.1
EMBL· GenBank· DDBJ
Genomic DNA

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