A0AAC9K6Y0 · A0AAC9K6Y0_9PROT
- Protein3-demethoxyubiquinol 3-hydroxylase
- Genecoq7
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids189 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
Catalytic activity
- a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = a 3-demethylubiquinol + A + H2O
a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol RHEA-COMP:10859 + CHEBI:17499 + CHEBI:15379 = a 3-demethylubiquinol RHEA-COMP:10914 + CHEBI:13193 + CHEBI:15377
Cofactor
Note: Binds 2 iron ions per subunit.
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 36 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 66 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 66 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 69 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 118 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 150 | Fe cation 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 150 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 153 | Fe cation 2 (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | 3-demethoxyubiquinol 3-hydroxylase activity | |
Molecular Function | metal ion binding | |
Biological Process | regulation of gene expression | |
Biological Process | regulation of reactive oxygen species metabolic process | |
Biological Process | ubiquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-demethoxyubiquinol 3-hydroxylase
- EC number
- Short namesDMQ hydroxylase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Granulibacter
Accessions
- Primary accessionA0AAC9K6Y0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)20,839
- Last updated2024-05-29 v1
- ChecksumD4BEDC58AD7FA0DD