A0AAC9IGF2 · A0AAC9IGF2_9BACI
- ProteinGlucosamine-6-phosphate deaminase
- GenenagB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids241 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Catalytic activity
- alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4+
Pathway
Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 67 | Proton acceptor; for enolization step | ||||
Sequence: D | ||||||
Active site | 136 | For ring-opening step | ||||
Sequence: N | ||||||
Active site | 138 | Proton acceptor; for ring-opening step | ||||
Sequence: H | ||||||
Active site | 143 | For ring-opening step | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glucosamine-6-phosphate deaminase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | N-acetylglucosamine metabolic process | |
Biological Process | N-acetylneuraminate catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucosamine-6-phosphate deaminase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0AAC9IGF2
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-229 | Glucosamine/galactosamine-6-phosphate isomerase | ||||
Sequence: DQLGKEAAAFIARTIKSKADAVLGLATGGTPIDTYKELIRLHQAEKLSFKQTRTVNLDEYVGLDPNHENSYMTYMRRHLFDHIDLPKDQYFLPNGAASQLEEECLRYDQLIEDLGGIDLQLLGIGQNGHIGFNEPGTPFDSKTHVVQLDEHTRKANARYFSSIDEVPTHAITMGIASILSSKKILLLASGKSKAEVIQYLEQTDVHPDFPASALKLHQDV |
Sequence similarities
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length241
- Mass (Da)26,922
- Last updated2024-05-29 v1
- Checksum555F64A2A6480027
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP017786 EMBL· GenBank· DDBJ | AOZ89190.1 EMBL· GenBank· DDBJ | Genomic DNA |