A0AAC9GD90 · A0AAC9GD90_NEIME
- Protein4-hydroxybenzoate octaprenyltransferase
- GeneubiA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids296 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
Catalytic activity
- 4-hydroxybenzoate + all-trans-octaprenyl diphosphate = 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate
Cofactor
Pathway
Cofactor biosynthesis; ubiquinone biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | 4-hydroxybenzoate octaprenyltransferase activity | |
Biological Process | ubiquinone biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-hydroxybenzoate octaprenyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria
Accessions
- Primary accessionA0AAC9GD90
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 51-71 | Helical | ||||
Sequence: LAVLAAFTIGTFLMRSAGCVI | ||||||
Transmembrane | 101-119 | Helical | ||||
Sequence: ALLLTAFLCLLAALCLIPL | ||||||
Transmembrane | 149-168 | Helical | ||||
Sequence: LYLGLAFSFGIPMAFAAVAG | ||||||
Transmembrane | 174-195 | Helical | ||||
Sequence: AWILFAANVLWTLAYDTVYAMA | ||||||
Transmembrane | 242-262 | Helical | ||||
Sequence: WAYWTAIPIVLLLQYRQYAAI | ||||||
Transmembrane | 274-294 | Helical | ||||
Sequence: FLANNRIGWVWFTAIFAHTFF |
Keywords
- Cellular component
Sequence
- Sequence statusComplete
- Length296
- Mass (Da)33,150
- Last updated2024-05-29 v1
- ChecksumA9B961CB2A0FC2FA