A0AAC9GD90 · A0AAC9GD90_NEIME

  • Protein
    4-hydroxybenzoate octaprenyltransferase
  • Gene
    ubiA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4-hydroxybenzoate octaprenyltransferase activity
Biological Processubiquinone biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxybenzoate octaprenyltransferase
  • EC number
  • Alternative names
    • 4-HB polyprenyltransferase

Gene names

    • Name
      ubiA
    • ORF names
      DE8555_0678

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DE8555
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria

Accessions

  • Primary accession
    A0AAC9GD90

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane51-71Helical
Transmembrane101-119Helical
Transmembrane149-168Helical
Transmembrane174-195Helical
Transmembrane242-262Helical
Transmembrane274-294Helical

Keywords

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the UbiA prenyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    296
  • Mass (Da)
    33,150
  • Last updated
    2024-05-29 v1
  • Checksum
    A9B961CB2A0FC2FA
MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLASDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEALLLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIPMAFAAVAGNVPPQAWILFAANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIAAVMLCHGGFTLLMAVLGAVIGAAWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLANNRIGWVWFTAIFAHTFFAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP012393
EMBL· GenBank· DDBJ
ANW91243.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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