A0AAC9CRU3 · A0AAC9CRU3_NEIME
- ProteinDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex
- GenesucB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids403 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO2.
Catalytic activity
- N6-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = CoA + N6-[(R)-S8-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2]
Cofactor
Note: Binds 1 lipoyl cofactor covalently.
Pathway
Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | oxoglutarate dehydrogenase complex | |
Molecular Function | dihydrolipoyllysine-residue succinyltransferase activity | |
Biological Process | L-lysine catabolic process to acetyl-CoA via saccharopine | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria
Accessions
- Primary accessionA0AAC9CRU3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length403
- Mass (Da)42,326
- Last updated2024-05-29 v1
- ChecksumE330B840D194B7DA