A0AAA9U2C6 · A0AAA9U2C6_BOVIN
- ProteinPhosphomannomutase
- GenePMM1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids220 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Catalytic activity
- alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
Cofactor
Pathway
Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 19 | Nucleophile | |||
Binding site | 19 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 21 | Proton donor/acceptor | |||
Binding site | 21 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 28 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 132 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 143 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 150 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | metal ion binding | |
Molecular Function | phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphomannomutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0AAA9U2C6
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length220
- Mass (Da)25,019
- Last updated2024-05-29 v1
- Checksum2505FD1238A9C87C
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q0VC17 | Q0VC17_BOVIN | PMM1 | 262 | ||
A0A3Q1MDY4 | A0A3Q1MDY4_BOVIN | PMM1 | 236 | ||
A0AAA9S1J1 | A0AAA9S1J1_BOVIN | PMM1 | 205 | ||
A0AAA9RZ33 | A0AAA9RZ33_BOVIN | PMM1 | 292 |
Keywords
- Technical term