A0AAA9U2C6 · A0AAA9U2C6_BOVIN

  • Protein
    Phosphomannomutase
  • Gene
    PMM1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

122020406080100120140160180200220
Type
IDPosition(s)Description
Active site19Nucleophile
Binding site19Mg2+ 1 (UniProtKB | ChEBI)
Active site21Proton donor/acceptor
Binding site21Mg2+ 1 (UniProtKB | ChEBI)
Binding site28alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site132alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site143alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site150alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmetal ion binding
Molecular Functionphosphomannomutase activity
Biological ProcessGDP-mannose biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomannomutase
  • EC number

Gene names

    • Name
      PMM1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0AAA9U2C6

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the eukaryotic PMM family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    220
  • Mass (Da)
    25,019
  • Last updated
    2024-05-29 v1
  • Checksum
    2505FD1238A9C87C
MAVTAEGARRKERVLCLFDVDGTLTPARQKIDPEVAAFLQKLRSRVQIGVVGGSDYSKIAEQLGEGDEVIEKFDYVFAENGTVQYKHGRLLSKQTIQNHLGEELLQDLINFCLRYMALLRLPKKRGTFIEFRNGMLNISPIGRSCTLEERIEFSELDKVPPTVSLSLRDLGHSTSLSLYFLIRERDPWWQAVLIQPVPFRTPALCHGCRHFCVFPALLAR

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q0VC17Q0VC17_BOVINPMM1262
A0A3Q1MDY4A0A3Q1MDY4_BOVINPMM1236
A0AAA9S1J1A0AAA9S1J1_BOVINPMM1205
A0AAA9RZ33A0AAA9RZ33_BOVINPMM1292

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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