Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0AAA9T7D8 · A0AAA9T7D8_BOVIN

  • Protein
    Dipeptidyl peptidase 3
  • Gene
    DPP3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

  • Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.
    EC:3.4.14.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

1750100200300400500600700
Type
IDPosition(s)Description
Binding site470Zn2+ (UniProtKB | ChEBI); catalytic
Active site471
Binding site475Zn2+ (UniProtKB | ChEBI); catalytic
Binding site528Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionaminopeptidase activity
Molecular Functiondipeptidyl-peptidase activity
Molecular Functionmetal ion binding
Molecular Functionmetalloexopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dipeptidyl peptidase 3
  • EC number
  • Alternative names
    • Dipeptidyl aminopeptidase III
    • Dipeptidyl peptidase III

Gene names

    • Name
      DPP3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0AAA9T7D8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase M49 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    750
  • Mass (Da)
    83,873
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    39B4F5F0565DA7BD6B47947987BCC44F
MGEPEAGSECAIRAAAAAGPMADTQYILPNDIGVSSLDCREAFRLLSSTERLYAHYLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQICGELMFSLESRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVGQDGKLSYEVRLASVLGTEPNLDSEMTSKLKSYEFQGSHFRVTRGDYAPILQKVVEQLEKAKAYAANSHQEQMLAQYIESFTQGSIEAHKKGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFEWLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFMQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPRVLEIFGFEGADAEDVVYVNWLNMVRAGLLALEFYTPEASSWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVHLDRDKIRTVGKPALERFLRRLQVLKSTGDVAGGRALYEGYAAVTDAPPECFLSLRDTVLLRKEARKLIVQPNTRLEGSEVQLLEYEASAAGLIRSFSERFLEDGPELEKILTQLATADAQCWKGPQ

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F2Z4F5F2Z4F5_BOVINDPP3744

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help