A0AAA9SF56 · A0AAA9SF56_BOVIN
- ProteinHexokinase-1
- GeneHK1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids865 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- D-fructose + ATP = D-fructose 6-phosphate + ADP + H+This reaction proceeds in the forward direction.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrial outer membrane | |
Molecular Function | ATP binding | |
Molecular Function | D-glucose binding | |
Molecular Function | hexokinase activity | |
Biological Process | glycolytic process | |
Biological Process | inflammatory response | |
Biological Process | innate immune response | |
Biological Process | intracellular glucose homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHexokinase-1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0AAA9SF56
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion outer membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 22-219 | Hexokinase N-terminal | |||
Domain | 226-459 | Hexokinase C-terminal | |||
Domain | 470-667 | Hexokinase N-terminal | |||
Domain | 674-739 | Hexokinase C-terminal | |||
Domain | 744-855 | Hexokinase C-terminal | |||
Sequence similarities
Belongs to the hexokinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length865
- Mass (Da)96,069
- Last updated2024-05-29 v1
- ChecksumD489AB0B1B1271BA
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A3S5ZPF0 | A0A3S5ZPF0_BOVIN | HK1 | 916 | ||
A0AAA9SUQ1 | A0AAA9SUQ1_BOVIN | HK1 | 787 | ||
A0AAA9T0D2 | A0AAA9T0D2_BOVIN | HK1 | 921 | ||
F1MZV1 | F1MZV1_BOVIN | HK1 | 839 | ||
A0AAA9TWG3 | A0AAA9TWG3_BOVIN | HK1 | 599 | ||
A0AAA9TZ81 | A0AAA9TZ81_BOVIN | HK1 | 969 | ||
A0AAA9S4V8 | A0AAA9S4V8_BOVIN | HK1 | 900 | ||
A0AAA9TTG0 | A0AAA9TTG0_BOVIN | HK1 | 877 | ||
A0A3Q1M0F0 | A0A3Q1M0F0_BOVIN | HK1 | 995 |
Keywords
- Technical term