A0AAA9S080 · A0AAA9S080_BOVIN
- ProteinAurora kinase
- GeneAURKA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids405 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 146 | ATP (UniProtKB | ChEBI) | |||
Binding site | 165 | ATP (UniProtKB | ChEBI) | |||
Binding site | 214-216 | ATP (UniProtKB | ChEBI) | |||
Active site | 259 | Proton acceptor | |||
Binding site | 263-264 | ATP (UniProtKB | ChEBI) | |||
Binding site | 277 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | centrosome | |
Cellular Component | cilium | |
Cellular Component | cytoplasm | |
Cellular Component | microtubule | |
Cellular Component | neuron projection | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | cell division | |
Biological Process | meiotic spindle organization | |
Biological Process | mitotic centrosome separation | |
Biological Process | mitotic spindle organization | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAurora kinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0AAA9S080
Proteomes
Organism-specific databases
Subcellular Location
Keywords
- Cellular component
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Cross-link | 261 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | |||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 13-45 | Disordered | |||
Compositional bias | 31-45 | Polar residues | |||
Region | 73-129 | Disordered | |||
Domain | 136-386 | Protein kinase | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length405
- Mass (Da)45,713
- Last updated2024-05-29 v1
- Checksum0B3F206060F7225D
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q2TA06 | AURKA_BOVIN | AURKA | 402 | ||
A0AAA9SES4 | A0AAA9SES4_BOVIN | AURKA | 417 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 31-45 | Polar residues | |||
Keywords
- Technical term