A0AAA9RZI6 · A0AAA9RZI6_BOVIN
- ProteinPyridoxal kinase
- GenePDXK
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids284 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively. PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
Catalytic activity
- pyridoxal + ATP = pyridoxal 5'-phosphate + ADP + H+This reaction proceeds in the forward direction.
Pathway
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxal: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxamine 5'-phosphate from pyridoxamine: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxine 5'-phosphate from pyridoxine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | pyridoxal kinase activity | |
Biological Process | pyridoxal 5'-phosphate salvage |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyridoxal kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0AAA9RZI6
Proteomes
Organism-specific databases
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length284
- Mass (Da)31,523
- Last updated2024-05-29 v1
- MD5 Checksum3B16E72A21378E0F3519237B1DDDE4AB
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q0II59 | PDXK_BOVIN | PDXK | 312 | ||
A0AAA9TN89 | A0AAA9TN89_BOVIN | PDXK | 284 | ||
A0AAA9SCI1 | A0AAA9SCI1_BOVIN | PDXK | 343 |
Keywords
- Technical term