Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0AAA9RZI6 · A0AAA9RZI6_BOVIN

  • Protein
    Pyridoxal kinase
  • Gene
    PDXK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively. PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.

Catalytic activity

Pathway

Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxal: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxamine 5'-phosphate from pyridoxamine: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxine 5'-phosphate from pyridoxine: step 1/1.

GO annotations

AspectTerm
Molecular Functionpyridoxal kinase activity
Biological Processpyridoxal 5'-phosphate salvage

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal kinase
  • EC number
  • Alternative names
    • Pyridoxine kinase

Gene names

    • Name
      PDXK

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    A0AAA9RZI6

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain74-246Pyridoxamine kinase/Phosphomethylpyrimidine kinase

Sequence similarities

Belongs to the pyridoxine kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    284
  • Mass (Da)
    31,523
  • Last updated
    2024-05-29 v1
  • MD5 Checksum
    3B16E72A21378E0F3519237B1DDDE4AB
MEEECRVLSIQSHVVRGYVGNRAATFPLQVLGFEVDAVNSVQFSNHTGYSHWKGQVLNSDELQELYDGLKLNSVNQYDYVLTVCDPVMGDQRDGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHTQEEALEVMDMLHSMGPDTVVITSSDLLSPRGSDYLMALGSQRTRAPDGSMVTQRIRMEMHKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELRMVQSKKDIESPEIVVQATVL

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q0II59PDXK_BOVINPDXK312
A0AAA9TN89A0AAA9TN89_BOVINPDXK284
A0AAA9SCI1A0AAA9SCI1_BOVINPDXK343

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help