A0AA96XBR9 · A0AA96XBR9_9GAMM

  • Protein
    Bifunctional adenosylcobalamin biosynthesis protein
  • Gene
    cobU
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site12-19GTP (UniProtKB | ChEBI)
Binding site42-44GTP (UniProtKB | ChEBI)
Active site58GMP-histidine intermediate
Binding site59-62GTP (UniProtKB | ChEBI)
Binding site70GTP (UniProtKB | ChEBI)
Binding site91GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional adenosylcobalamin biosynthesis protein
  • EC number

Gene names

    • Name
      cobU
    • ORF names
      QT397_14040

Organism names

  • Taxonomic identifier
  • Strain
    • MKSA007
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Cellvibrionales > Microbulbiferaceae > Microbulbifer

Accessions

  • Primary accession
    A0AA96XBR9

Family & Domains

Sequence similarities

Belongs to the CobU/CobP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    182
  • Mass (Da)
    19,703
  • Last updated
    2024-03-27 v1
  • Checksum
    6059BAC6A93E3ED6
MSSSIGVHLVLGGARSGKSRLAQQRAEQWLSSSSDGGLTYLATATAGDQEMSTRIARHREDRDHRWQTLEEPIALAEALVTAPESHCVLVDCLTLWLSNCLHQGVLEREQGALLQCIDQRRTLANGNTPPWIFVSNEVGSGIVPLGQLSREFVDAAGWLHQALAERADSVTLAIAGLPLTVK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP128433
EMBL· GenBank· DDBJ
WNZ58411.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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