A0AA96X6G8 · A0AA96X6G8_9GAMM

  • Protein
    ATP-dependent dethiobiotin synthetase BioD
  • Gene
    bioD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site13-18ATP (UniProtKB | ChEBI)
Binding site17Mg2+ (UniProtKB | ChEBI)
Active site38
Binding site42substrate
Binding site55ATP (UniProtKB | ChEBI)
Binding site55Mg2+ (UniProtKB | ChEBI)
Binding site117Mg2+ (UniProtKB | ChEBI)
Binding site117-120ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functiondethiobiotin synthase activity
Molecular Functionmagnesium ion binding
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent dethiobiotin synthetase BioD
  • EC number
  • Alternative names
    • DTB synthetase
      (DTBS
      )
    • Dethiobiotin synthase

Gene names

    • Name
      bioD
    • ORF names
      QT397_05265

Organism names

  • Taxonomic identifier
  • Strain
    • MKSA007
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Cellvibrionales > Microbulbiferaceae > Microbulbifer

Accessions

  • Primary accession
    A0AA96X6G8

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the dethiobiotin synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    232
  • Mass (Da)
    24,457
  • Last updated
    2024-03-27 v1
  • Checksum
    1048A0962FD22641
MAKTYFIAGTDTEVGKTYVSAALLSAAAEAGLQTAAVKPVASGCEHTDDGLRNEDALLLQEAMTLKLPYQQVNPFALEPAIAPHIAAAEVGKQLNVARMAGVCRGVMSAGADLVLIEGAGGWRTPLGPRSFLSQLPRELNLPVILVVGMQLGCINHALLTVEAIRRDGLPLVGWVANFVRGEGMARAEENLHTLKALLPAPLLGSLPFDSAANYRNAAQYLDIDGLIAQADH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP128433
EMBL· GenBank· DDBJ
WNZ56770.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help