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A0AA96WN49 · A0AA96WN49_9CYAN

Function

Catalytic activity

  • Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.
    EC:3.2.2.31 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Features

Showing features for binding site.

141150100150200250300350400
TypeIDPosition(s)Description
Binding site3008-oxo-dGTP (UniProtKB | ChEBI)
Binding site311-3148-oxo-dGTP (UniProtKB | ChEBI)
Binding site314Mg2+ (UniProtKB | ChEBI)
Binding site334Mg2+ (UniProtKB | ChEBI)
Binding site3968-oxo-dGTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
Molecular Function8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
Molecular Functionadenine/guanine mispair binding
Molecular Functionmetal ion binding
Molecular Functionoxidized purine DNA binding
Molecular Functionpurine-specific mismatch base pair DNA N-glycosylase activity
Biological Processbase-excision repair
Biological Processmismatch repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenine DNA glycosylase
  • EC number

Gene names

    • Name
      mutY
    • ORF names
      HJG54_18665

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NK1-12
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Leptolyngbyales > Leptolyngbyaceae > Leptolyngbya group > Leptolyngbya

Accessions

  • Primary accession
    A0AA96WN49

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-26Disordered
Domain278-407Nudix hydrolase

Sequence similarities

Belongs to the Nth/MutY family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    411
  • Mass (Da)
    46,130
  • Last updated
    2024-03-27 v1
  • MD5 Checksum
    159E742BC2D8BBF89D807EF424FADFDE
MTANPIHSNSRALSPKSPKSTKVSTRAKDSSGVWLLHPDQAGVQAARYQVLLNSPVVVELRQLLLCWYAVHGRSLPWRQTRDPYAIWVSEIMLQQTQVKTVIPYYERWLAQFPTIAALAAANQQQVLKAWQGLGYYARARNLHQAAQQLMQQGGQFPTSLEAVLTLPGIGRTTAGGILSAAFNQPTPILDGNVKRVLARLLALEIPPNRATSLLWQASELLLDLDNPRDFNQALMDLGATLCTPKQPACLLCPWNQYCHAYRTNMQNELPVNETRTAIPHKQIGVAVIWNDQGQILIDRRRQDGLLGGLWEFPGGKLEANETIQACIRREILEELGIEIEVGDHLITIDHAYSHFHVTLNVYHCRHISGEPQPLECDEARWVDLDELDQFPFPKANVTIIEALQQFKQVGS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP053586
EMBL· GenBank· DDBJ
WNZ24671.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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