A0AA96UUX0 · A0AA96UUX0_9CUCU

  • Protein
    NADH-ubiquinone oxidoreductase chain 5
  • Gene
    NAD5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      NAD5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Curculionidae > Molytinae > Tranes

Accessions

  • Primary accession
    A0AA96UUX0

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-29Helical
Transmembrane49-73Helical
Transmembrane85-106Helical
Transmembrane150-168Helical
Transmembrane180-204Helical
Transmembrane245-263Helical
Transmembrane270-288Helical
Transmembrane294-316Helical
Transmembrane337-355Helical
Transmembrane375-400Helical
Transmembrane421-443Helical
Transmembrane449-471Helical
Transmembrane492-513Helical
Transmembrane554-571Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain40-88NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain105-387NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain391-571NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    572
  • Mass (Da)
    65,605
  • Last updated
    2024-03-27 v1
  • Checksum
    F2DF2DF334CDF023
MFLLCNVCFLIFLIFSLIFYFLGLCFLNAELEIFTEWTVLSFNSISVVMLMYFDWNSLMFMSFVFFISSMIIKYSDEYMLGDKKLARFIMLMVLFVFSMMLLIFSLNMVSLLLGWDGLGLVSYLLVVYYQNVKSYNAGMLTALSNRIGDAALLMSIAWMMHLGSWNFFSYLEYMKEHKSMYVAVLLVILAAITKSAQIPFSSWLPAAMAAPTPVSSLVHSSTLVTAGVYLLFRFSEAMSNTMFDILLYISLFTMFMAGLSANYEYDLKKIIALSTLSQLGMMISIMCLGSDDLAFFHLLIHALFKALLFMCAGAMIHNLGNCQDIRYMGGLTHFMPLTCSCMNISNFALCGLPFLSGFYSKDLVAEILSMDYSGILIYIVFFVSVGLTVSYSMRLSYYIFFGEFNSLSLNYLNDSNNKIMLKGMMGLVFLVIFKGSVLMWLLFPSPQIIILPFFMKIFTLIVIMFGGFLGYELSQTSYAYSQKTMKMFNMSVFLSNMWNLPILSTLGINSFFLRLGKLFTKKFDQGWFEYYGSKKLFSLFKKTTQFFQMLSRNHLKLFLLVMFLMFLFVVLL

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue572

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OP135309
EMBL· GenBank· DDBJ
WNX92235.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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