A0AA88VDJ2 · A0AA88VDJ2_9ASTE
- ProteinDNA-(apurinic or apyrimidinic site) endonuclease 2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids890 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Probably binds two magnesium or manganese ions per subunit.
Features
Showing features for active site, binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 157 | ||||
Active site | 198 | Proton donor/acceptor | |||
Binding site | 198 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 200 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 200 | Transition state stabilizer | |||
Site | 269 | Important for catalytic activity | |||
Binding site | 326 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 327 | Proton acceptor | |||
Binding site | 327 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 327 | Interaction with DNA substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | phosphoric diester hydrolase activity | |
Molecular Function | zinc ion binding | |
Biological Process | base-excision repair |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDNA-(apurinic or apyrimidinic site) endonuclease 2
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > campanulids > Escalloniales > Escalloniaceae > Escallonia
Accessions
- Primary accessionA0AA88VDJ2
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length890
- Mass (Da)98,868
- Last updated2024-03-27 v1
- Checksum702B2925C0080655
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAVXUP010001965 EMBL· GenBank· DDBJ | KAK3006640.1 EMBL· GenBank· DDBJ | Genomic DNA |