A0AA45TVT6 · A0AA45TVT6_9BACT

  • Protein
    Bifunctional ligase/repressor BirA
  • Gene
    birA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for dna binding, binding site.

133350100150200250300
TypeIDPosition(s)Description
DNA binding27-46H-T-H motif
Binding site98-100biotin (UniProtKB | ChEBI)
Binding site122biotin (UniProtKB | ChEBI)
Binding site192biotin (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionbiotin--[biotin carboxyl-carrier protein] ligase activity
Molecular FunctionDNA binding
Biological Processprotein modification process
Biological Processregulation of DNA-templated transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional ligase/repressor BirA
  • Alternative names
    • Biotin--[acetyl-CoA-carboxylase] ligase
      (EC:6.3.4.15
      ) . EC:6.3.4.15 (UniProtKB | ENZYME | Rhea)
    • Biotin--protein ligase
    • Biotin-[acetyl-CoA carboxylase] synthetase

Gene names

    • Name
      birA
    • ORF names
      D7Y11_42020

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AB018
  • Taxonomic lineage
    Bacteria > Myxococcota > Myxococcia > Myxococcales > Cystobacterineae > Myxococcaceae > Corallococcus

Accessions

  • Primary accession
    A0AA45TVT6

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain75-265BPL/LPL catalytic

Sequence similarities

Belongs to the biotin--protein ligase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    333
  • Mass (Da)
    36,156
  • Last updated
    2024-01-24 v1
  • Checksum
    4AEA154AEAC86704
MEMTNELTQDARILNFLAEGGEGFISGEALSNRLGLSRTAVWKHVEALRLKGYRIEAVPAKGYRLVGRPDRLSALELHPLLATRAVGRVLHHHDTIGSTNAAAFRLAQDGAAHGTVVVAEQQTAGKGRRGRAWVSPPNLNLYFSAILRPELPPQRAPELTLVAAVALAETLRDAGADAAIKWPNDVQIAGKKVAGILTELSAEPERVHFVIVGVGVNLNSGDEHFPDELRATATSVALAQGRPVARAPFTAALWNRLETWLDTYLATGFDAVRTRWKALSSTLGVPVRVRTDRGDWEGFAEDIDPTGALMVRMADGRVERVLAGDVEQLRPQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RAWR01000388
EMBL· GenBank· DDBJ
RUO87188.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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