A0AA44HJB3 · A0AA44HJB3_9BACT
- ProteinPhosphatidylcholine 1-acylhydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids329 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+
Cofactor
Note: Binds 1 Ca2+ ion per monomer.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 161 | Ca2+ 1 (UniProtKB | ChEBI); in dimeric form | |||
Active site | 196 | Proton acceptor | |||
Active site | 198 | Nucleophile | |||
Binding site | 208 | Ca2+ 1 (UniProtKB | ChEBI); in dimeric form | |||
Binding site | 243 | Ca2+ 1 (UniProtKB | ChEBI); in dimeric form | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell outer membrane | |
Molecular Function | metal ion binding | |
Molecular Function | phospholipase activity | |
Biological Process | lipid catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphatidylcholine 1-acylhydrolase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Campylobacteraceae > Campylobacter
Accessions
- Primary accessionA0AA44HJB3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell outer membrane ; Multi-pass membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5041341134 | 23-329 | Phosphatidylcholine 1-acylhydrolase | ||
Interaction
Subunit
Homodimer; dimerization is reversible, and the dimeric form is the active one.
Structure
Sequence
- Sequence statusComplete
- Length329
- Mass (Da)39,172
- Last updated2024-01-24 v1
- ChecksumB07F04B407196EF9
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MJWZ01000029 EMBL· GenBank· DDBJ | OEW23834.1 EMBL· GenBank· DDBJ | Genomic DNA |