A0AA44HHF9 · A0AA44HHF9_9BACT

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

115620406080100120140
TypeIDPosition(s)Description
Active site113
Active site130

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      AJ939_04930

Organism names

  • Taxonomic identifier
  • Strain
    • BCW_6889
  • Taxonomic lineage
    Bacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Campylobacteraceae > Campylobacter

Accessions

  • Primary accession
    A0AA44HHF9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-25Helical
Transmembrane62-79Helical
Transmembrane91-108Helical
Transmembrane120-142Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    156
  • Mass (Da)
    18,320
  • Last updated
    2024-01-24 v1
  • Checksum
    144EDE5ACC95A23C
MAKTFKFIFYFWGVFVLVFALDQWVKSLTLAGLRWQSEYLDLTYALNTGVAFSMLSFLEHNLKYLHLALIGVLFIYLFWQKTLLKTHNIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKWFNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MJWZ01000055
EMBL· GenBank· DDBJ
OEW21192.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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