A0AA43QRL2 · A0AA43QRL2_9LECA

  • Protein
    Pescadillo homolog
  • Gene
    SAC1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Cellular Componentnucleoplasm
Cellular ComponentPeBoW complex
Cellular Componentpreribosome, large subunit precursor
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionphosphatase activity
Molecular Functionribonucleoprotein complex binding
Molecular FunctionRNA binding
Molecular Functiontetrahydrofolylpolyglutamate synthase activity
Biological Processcellular lipid metabolic process
Biological Processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Processone-carbon metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Pescadillo homolog
  • Alternative names
    • Nucleolar protein 7 homolog

Gene names

    • Name
      SAC1
    • Synonyms
      NOP7
    • ORF names
      OHK93_002087

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LIQ254RAFAR
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Lecanoromycetes > OSLEUM clade > Lecanoromycetidae > Lecanorales > Lecanorineae > Ramalinaceae > Ramalina

Accessions

  • Primary accession
    A0AA43QRL2

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane587-608Helical
Transmembrane620-639Helical

Keywords

Interaction

Subunit

Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain117-519SAC
Region1441-1544Disordered
Domain1546-1657BRCT
Region1669-1882Disordered
Compositional bias1687-1709Acidic residues
Compositional bias1746-1761Acidic residues
Compositional bias1762-1786Basic and acidic residues
Compositional bias1814-1843Basic and acidic residues
Compositional bias1850-1873Basic and acidic residues

Sequence similarities

Belongs to the folylpolyglutamate synthase family.
Belongs to the pescadillo family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,882
  • Mass (Da)
    209,622
  • Last updated
    2024-01-24 v1
  • Checksum
    D12BDA6AB1647409
MRHLVPFRDINVHASASHYAFTSPSSPGAQTLVVDRPSGDLRLSDGPLLGTKRVSSIAGILGMIKLRLDKYIIVITKAQPMGRLKGHMVYRVVSTEFFPLRERSLHDPDEDTYLSLLKTSLKNGPMYFSYSCDLTNSFQRQAQSDPSQPLWKRADDRFFWNRFVQSDLIDLATGGGSASGLRGGAQPGADPFILPVMFGMMRITSTKVKGTPFSFTLITRRSRHRAGTRYLTRGINDLGHVGNYNETEQIVILNEGEAIPSGFAGGGGMQNGRVDNDGHETQVMSYIQTRGSVPVYWAEINTLHYTPNLQVRAVETAIDAARKHFDEQIRLYGDNFLVNLVNQRGREDKVKRAYEQMVRLLVSSPDEATQSDYVTDEKIHIVEASEKHQGYDRLHYVYFDFHNETKGLKWHRAQLLLDQLTDGLRKGQYFRGVDMPADPQGRLEVRNQQTAVVRTNCMDCLDRTNVVQTMLARWTLTRQLTDIGVLLPGESADDDAAFAHFFRNVWADNADVVSKSYSGTGALKTDFTRTGERTRAGAMQDLNNSLTRYVKNNFGDGPRQDAFDLFLGNYHPDPVGTNLVFQDRRPVLVQAIPYVLAACIFFVLVTGLTRTSPETTIWPLRVFAFVCMAVGAWCGRFVWGNGMLYVNWPKLNTPRWAAEGFQDTMSRDAIAALNTLQSNATVVEAVRKSGGRMNETAKAEMLDWVERLGYEPSDFNRLNPIHIAGTKGKGSTSTFISSILAQYLPSPKHPNPVIHKIGLYTSPHLRFVRERIQINNEPLTEDDFAKYFFETWDRFESSARQRSEPPDVTAKPAYFRFLTLMAFHTYLSEGVDTAIIECGVGGEYDSTNILIRPTVTAITSLGIDHTAILGNTIEEIAWHKGGIMKQSAPCFTAPQAASAFAVLEKRATEVPTKLTLVTPFPELSKIKLGLAGTFQSINASLALTIAGAHLLALGYRQMIEKTGLPIEVVRGLESAHLSGRCETRLEGKMTWCMDSGHTLESIALAATWFGSEIKKASLPKKRRRILLFNQQTRDASALATRLYQTLDAAAGADKEQPFTHAVFCSNKTFQQAGFRPDLQNMNVTGSSVDNLEVQKKLAETWKALDAKTTVEVRGSIEEAVEWCRGVASADAEEEEGAMVLVTGSVHLTKREFLGKAFCRHTSKVFDIDIESGMRTYSRSIEEIWAKSRRRARTSGQAKNFITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKVSKSSTPSTTFYYTKDVQYLLHEPLLAKFRDHKALSKKIAKSLGRGEVGDAARLEKHGGPKLTLDHVIKERYPTFVDALRDLDDALSLLSLFANLPSTVNVPGKTIQLCQRLCLEFQHYLIKTNALRKSFLSIKGIYYQATIQGQDILWLVPYKFVQRVTGDVDFRIMGTFVEFYTTLLGFVNFRLYTSIGLVYPPKFDTKSDEQGGELSAFTLEGRNIGGADQSKEPATNGDDAASQTNGVHEIPAEVQRQIDSIQEPPENDKEAPLTADPLSSAIPDNAAPPTDVIDTFQPITQDADILPQPAPSTTQTSTLFAPFTFYLSRETPRQPLEFLLRAFGCTRIGWDLTLGSGAFTANENDTSITHQIVDRPPISTPTIDEATGAMVSKGAMRMPGRTYVQPQWVWDCINEVRLLRPDLYAPGATLPPHLSPFVKPTKGGYDPTAPLAEQEREGEAEDDEDIAAVDDDDNEDDSTPQIAMGKAPADDEAILSSGEEAGKDLHGMAIATGDDSPGDDDDDKDDESDVFAGFESEAHDSDTGLTPELLHQRELEAEATGGVALNGSSAAKKGILKNSGGADADVEAKKQRSKARQRKQRDEDEELERRKMMLGRKKRKLVEKMMYGNKMRDAEAEQLRRKRRKMERSKP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1687-1709Acidic residues
Compositional bias1746-1761Acidic residues
Compositional bias1762-1786Basic and acidic residues
Compositional bias1814-1843Basic and acidic residues
Compositional bias1850-1873Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPUFD010000013
EMBL· GenBank· DDBJ
MDI1490882.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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