A0AA43QRL2 · A0AA43QRL2_9LECA
- ProteinPescadillo homolog
- GeneSAC1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1882 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | nucleoplasm | |
Cellular Component | PeBoW complex | |
Cellular Component | preribosome, large subunit precursor | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | phosphatase activity | |
Molecular Function | ribonucleoprotein complex binding | |
Molecular Function | RNA binding | |
Molecular Function | tetrahydrofolylpolyglutamate synthase activity | |
Biological Process | cellular lipid metabolic process | |
Biological Process | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | |
Biological Process | one-carbon metabolic process |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended namePescadillo homolog
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Lecanoromycetes > OSLEUM clade > Lecanoromycetidae > Lecanorales > Lecanorineae > Ramalinaceae > Ramalina
Accessions
- Primary accessionA0AA43QRL2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 587-608 | Helical | ||||
Sequence: VLVQAIPYVLAACIFFVLVTGL | ||||||
Transmembrane | 620-639 | Helical | ||||
Sequence: LRVFAFVCMAVGAWCGRFVW |
Keywords
- Cellular component
Interaction
Subunit
Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 117-519 | SAC | ||||
Sequence: LKTSLKNGPMYFSYSCDLTNSFQRQAQSDPSQPLWKRADDRFFWNRFVQSDLIDLATGGGSASGLRGGAQPGADPFILPVMFGMMRITSTKVKGTPFSFTLITRRSRHRAGTRYLTRGINDLGHVGNYNETEQIVILNEGEAIPSGFAGGGGMQNGRVDNDGHETQVMSYIQTRGSVPVYWAEINTLHYTPNLQVRAVETAIDAARKHFDEQIRLYGDNFLVNLVNQRGREDKVKRAYEQMVRLLVSSPDEATQSDYVTDEKIHIVEASEKHQGYDRLHYVYFDFHNETKGLKWHRAQLLLDQLTDGLRKGQYFRGVDMPADPQGRLEVRNQQTAVVRTNCMDCLDRTNVVQTMLARWTLTRQLTDIGVLLPGESADDDAAFAHFFRNVWADNADVVSKSYSG | ||||||
Region | 1441-1544 | Disordered | ||||
Sequence: QGGELSAFTLEGRNIGGADQSKEPATNGDDAASQTNGVHEIPAEVQRQIDSIQEPPENDKEAPLTADPLSSAIPDNAAPPTDVIDTFQPITQDADILPQPAPST | ||||||
Domain | 1546-1657 | BRCT | ||||
Sequence: QTSTLFAPFTFYLSRETPRQPLEFLLRAFGCTRIGWDLTLGSGAFTANENDTSITHQIVDRPPISTPTIDEATGAMVSKGAMRMPGRTYVQPQWVWDCINEVRLLRPDLYAP | ||||||
Region | 1669-1882 | Disordered | ||||
Sequence: VKPTKGGYDPTAPLAEQEREGEAEDDEDIAAVDDDDNEDDSTPQIAMGKAPADDEAILSSGEEAGKDLHGMAIATGDDSPGDDDDDKDDESDVFAGFESEAHDSDTGLTPELLHQRELEAEATGGVALNGSSAAKKGILKNSGGADADVEAKKQRSKARQRKQRDEDEELERRKMMLGRKKRKLVEKMMYGNKMRDAEAEQLRRKRRKMERSKP | ||||||
Compositional bias | 1687-1709 | Acidic residues | ||||
Sequence: REGEAEDDEDIAAVDDDDNEDDS | ||||||
Compositional bias | 1746-1761 | Acidic residues | ||||
Sequence: DSPGDDDDDKDDESDV | ||||||
Compositional bias | 1762-1786 | Basic and acidic residues | ||||
Sequence: FAGFESEAHDSDTGLTPELLHQREL | ||||||
Compositional bias | 1814-1843 | Basic and acidic residues | ||||
Sequence: DADVEAKKQRSKARQRKQRDEDEELERRKM | ||||||
Compositional bias | 1850-1873 | Basic and acidic residues | ||||
Sequence: RKLVEKMMYGNKMRDAEAEQLRRK |
Sequence similarities
Belongs to the folylpolyglutamate synthase family.
Belongs to the pescadillo family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,882
- Mass (Da)209,622
- Last updated2024-01-24 v1
- ChecksumD12BDA6AB1647409
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1687-1709 | Acidic residues | ||||
Sequence: REGEAEDDEDIAAVDDDDNEDDS | ||||||
Compositional bias | 1746-1761 | Acidic residues | ||||
Sequence: DSPGDDDDDKDDESDV | ||||||
Compositional bias | 1762-1786 | Basic and acidic residues | ||||
Sequence: FAGFESEAHDSDTGLTPELLHQREL | ||||||
Compositional bias | 1814-1843 | Basic and acidic residues | ||||
Sequence: DADVEAKKQRSKARQRKQRDEDEELERRKM | ||||||
Compositional bias | 1850-1873 | Basic and acidic residues | ||||
Sequence: RKLVEKMMYGNKMRDAEAEQLRRK |
Keywords
- Technical term