A0AA42GTB8 · A0AA42GTB8_9HYPH

  • Protein
    UDP-N-acetylmuramoylalanine--D-glutamate ligase
  • Gene
    murD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site121-127ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functiontetrahydrofolylpolyglutamate synthase activity
Molecular FunctionUDP-N-acetylmuramoylalanine-D-glutamate ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylmuramoylalanine--D-glutamate ligase
  • EC number
  • Alternative names
    • D-glutamic acid-adding enzyme
    • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase

Gene names

    • Name
      murD
    • ORF names
      N7376_01250

Organism names

  • Taxonomic identifier
  • Strain
    • GD04153
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella

Accessions

  • Primary accession
    A0AA42GTB8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain119-297Mur ligase central
Domain319-434Mur ligase C-terminal

Sequence similarities

Belongs to the MurCDEF family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    467
  • Mass (Da)
    48,822
  • Last updated
    2024-01-24 v1
  • Checksum
    0C3976297675F937
MIPITALKDKTVALFGLGGSGIATAKAILGGGAKVIAWDDNPDSVARAQSAGIATGDLRQADWSQFAAFVLSPGVPLTHPKPHWTVDLAHAAGVEIIGDVELFVRERNHIAPDCPFIAITGTNGKSTTTALIAHIIKASGRDMQLGGNIGTAILTLEPPQANRFYVVECSSYQIDLAPSLNPTAGILLNLTPDHLDRHGSMENYAAIKERLVAASDTAIVGVDDQYCEAIADRLYRDGVHVVRISKEKQLGKGYFADGAKLLWAQDGEVDEIASLEGIGSLRGAHNAQNALAAIAACLSVGLSLEEIHAGLKSFPGLAHRMEQVGHRGKVLFVNDSKATNAEATAPALSSFPQNIYWIAGGVPKAGGIASLAGFFPRIAKAYLIGEAAAQFAATLGDAAPFEISDTLAVAVEHAARDAGNDAAPEPVVLLSPACASFDQFQNFEKRGDAFRSAVLALPGVERIGGES

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAODYY010000001
EMBL· GenBank· DDBJ
MDH0122613.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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