A0AA39HRY1 · A0AA39HRY1_9BILA
- ProteinO-acyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids634 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2OThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoAThis reaction proceeds in the forward direction.
- 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoAThis reaction proceeds in the forward direction.
- 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoAThis reaction proceeds in the forward direction.
- all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- hexadecan-1-ol + hexadecanoyl-CoA = hexadecanyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
- hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoAThis reaction proceeds in the forward direction.
- hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoAThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism; glycerolipid metabolism.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 402 | |||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | diacylglycerol O-acyltransferase activity | |
Biological Process | triglyceride biosynthetic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameO-acyltransferase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Tylenchina > Panagrolaimomorpha > Strongyloidoidea > Steinernematidae > Steinernema
Accessions
- Primary accessionA0AA39HRY1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 75-96 | Helical | ||||
Sequence: FVNLAVLLLVVSNGRVALENLI | ||||||
Transmembrane | 116-137 | Helical | ||||
Sequence: WNWPNATLVVLANISVFVVFFM | ||||||
Transmembrane | 149-173 | Helical | ||||
Sequence: SFACIVYVVLLTVHMGGPVLVTLAL | ||||||
Transmembrane | 179-204 | Helical | ||||
Sequence: YSAVALSIFVVTALKLISYAHVNYWC | ||||||
Transmembrane | 269-288 | Helical | ||||
Sequence: LGEMVGLTFLIIALNQQWVV | ||||||
Transmembrane | 319-340 | Helical | ||||
Sequence: LIWLLFFYLLFHSTLNFLAELL | ||||||
Transmembrane | 388-410 | Helical | ||||
Sequence: LTAALAVFFISALLHEYLVSVPL | ||||||
Transmembrane | 416-435 | Helical | ||||
Sequence: WAYYGMMAQVPLGLVTDYIL | ||||||
Transmembrane | 442-461 | Helical | ||||
Sequence: NIVVWLSLILGQPMAILIMA |
Keywords
- Cellular component
Interaction
Subunit
Homodimer or homotetramer; both forms have similar enzymatic activities.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-38 | Disordered | ||||
Sequence: MAEAAVHTDSSGSNEQNGLRRRHPSTSSQHSSVGVPSR | ||||||
Compositional bias | 7-38 | Polar residues | ||||
Sequence: HTDSSGSNEQNGLRRRHPSTSSQHSSVGVPSR | ||||||
Compositional bias | 591-616 | Polar residues | ||||
Sequence: VASKNSSPAKVSKPPTVIAKTANQSS | ||||||
Region | 591-634 | Disordered | ||||
Sequence: VASKNSSPAKVSKPPTVIAKTANQSSFDATKRKRRMPGGAIFAD |
Sequence similarities
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length634
- Mass (Da)71,898
- Last updated2024-01-24 v1
- Checksum3F39259278FF94CA
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0AA39HQU0 | A0AA39HQU0_9BILA | QR680_004766 | 481 | ||
A0AA39HQX9 | A0AA39HQX9_9BILA | QR680_004766 | 611 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 7-38 | Polar residues | ||||
Sequence: HTDSSGSNEQNGLRRRHPSTSSQHSSVGVPSR | ||||||
Compositional bias | 591-616 | Polar residues | ||||
Sequence: VASKNSSPAKVSKPPTVIAKTANQSS |
Keywords
- Technical term