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A0AA37X9P1 · A0AA37X9P1_9MICO

  • Protein
    Homoserine dehydrogenase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functionhomoserine dehydrogenase activity
Molecular FunctionNADP binding
Biological Processmethionine biosynthetic process
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Homoserine dehydrogenase
  • EC number

Gene names

    • ORF names
      GCM10025874_01460

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NBRC 112289
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Arenivirga

Accessions

  • Primary accession
    A0AA37X9P1

Proteomes

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain13-130Aspartate/homoserine dehydrogenase NAD-binding
Domain138-305Homoserine dehydrogenase catalytic
Region304-390Disordered
Compositional bias311-325Polar residues
Compositional bias344-377Polar residues

Sequence similarities

Belongs to the homoserine dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    390
  • Mass (Da)
    40,431
  • Last updated
    2024-01-24 v1
  • MD5 Checksum
    5216FD2D8BD22514CB7420E5CA28DEF9
MIEYRTLRVALLGAGSVGSQVAAQLIARADELASRAGAGIELAGIAVRDLDAPRDADLPRELLTTDPHELILSSDIVVELMGGIESARTLILEALGTGADVVTANKALLAAHGPELFAAAEQVGAQLHYEAAVAGAIPIIRPLRDSLAGDRVQRILGIVNGTTNYILDEMHTKGLGLEDALAVATELGYAEADPTADIEGHDAAAKAAILAGLAFHTTVPLESVHCEGITAVTAEQIESAKQAGYVVKLLAICEQLDSGVSARVHPALVPAAHPLASVHGANNAVFVQAEAAGDLMFYGAGAGASRPPARCWATSSRSRGGTSPAGRASRSRPARPWASRPSAASRPATRSRSRSRTGRACWLRSPGSSTSRASRSRPCCSRAPPAPLRW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias311-325Polar residues
Compositional bias344-377Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BSUL01000001
EMBL· GenBank· DDBJ
GMA26893.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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