A0AA37JT39 · A0AA37JT39_BACUN

  • Protein
    6,7-dimethyl-8-ribityllumazine synthase
  • Gene
    ribH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site315-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site65-675-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site89-915-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site94-95(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site97Proton donor
Binding site1225-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site136(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • ORF names
      CE91St12_17110

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CE91-St12
  • Taxonomic lineage
    Bacteria > Bacteroidota > Bacteroidia > Bacteroidales > Bacteroidaceae > Bacteroides

Accessions

  • Primary accession
    A0AA37JT39

Proteomes

Subcellular Location

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    164
  • Mass (Da)
    17,688
  • Last updated
    2024-01-24 v1
  • Checksum
    C8947A4E621312F1
MATAYHNLSDYDFSTVPSAEKMKFGIVVSEWNYNITGALLKGAIDTLKKHGAKDENILVKTVPGSFELTFGANQLIEYSEVDAVIAIGCVVRGDTPHFDYVCMGATQGITQLNASGDVPVIYGLITTNTMEQAEDRAGGKLGNKGDECAITAIKMIDFAWSLQK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BQNL01000001
EMBL· GenBank· DDBJ
GKH13501.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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