A0AA37JS94 · A0AA37JS94_9FIRM

  • Protein
    Penicillin-binding protein 1A
  • Gene
    mrcA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

function

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncarboxypeptidase activity
Molecular Functionpenicillin binding
Biological Processproteolysis
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Penicillin-binding protein 1A
  • EC number

Gene names

    • Name
      mrcA
    • ORF names
      CE91St55_63740

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CE91-St55
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Hungatella

Accessions

  • Primary accession
    A0AA37JS94

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein
Membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane26-53Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain85-264Glycosyl transferase family 51
Domain442-728Penicillin-binding protein transpeptidase
Region649-679Disordered
Compositional bias656-679Polar residues
Region848-895Disordered
Compositional bias870-884Polar residues

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    895
  • Mass (Da)
    97,007
  • Last updated
    2024-01-24 v1
  • Checksum
    1E84DA5F240C36AF
MNYGKHETEKKIKSVNSKAKKYTSRVFLAFLKSLFVLCLFCLVVAGSIGFGMVKGIIDNAPDVDIATIVPNEYATTVYDSAGNVTETLVTAGSNREEASYDELPGNLINAFVAYEDARFWEHNGIDLRSIMRAVKGVLTGDSSAGGGSTITQQLIKNSVFGGGMEKSFGERLERKMQEWYLAVKLDSAMSKEQIITNYLNTINLGKNSLGVKVAARRYFNKEVSDLTLSECAVLAGITQNPSKFNPVTGQKANSDKQKVILQYMVDQGYISKDEQEEALADDVYSRIQDVEIVTKETSTPYSYFTDELVEQVQDAMKEKLGYTNTQAHNMLYSGGLSIYTTQDPTIQSIVDEEINNPDNYSAARYSIEYRLSVTGADGSTTHYSEENLKRYHRDNGDSSYDGLYDSEEEIQADIENYKNSLLKEGDTIIGESLHKTLQPQASFVIMDQKTGQVKAIAGGRGEKTASLTLNRASNTLRQPGSTFKVLTAFAPAMDTCGATLGTVYYDSVYTVGKKTFSNWYSSGYQGYSSIRDGIIYSMNIVAVRCLMETVTPQLGVEYAKNFGITSLTDTDYNAALALGGITDGVSNLEMTAAYATIANGGVYTKPVFFTKIIDHNGKVLIDNTPETHRVLKDSTAFLLTDAMADSMESSRKFARPGAGPSSTSSSANIPGMSNAGKSGTTTSNNDIWFVGYTPYYTAGIWGGCDNNQKLTKKNGGTSFHKAIWKKIMTRVHEGMSDPGFTVPDSVETAQICRKSGKLPVAGVCTNDPRGNAVYTEYFAKGTVPTDVCNNHVRATVCAESHCLPTPFCPERTTAVFMALPAGEEGTTDDSVFAMPGYCPIHTEASVIIPPSDDTGMPETVAPGTLPYGPGYVSPNTQTSPAPPAGSPVQMSPGGQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias656-679Polar residues
Compositional bias870-884Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BQNJ01000002
EMBL· GenBank· DDBJ
GKH04393.1
EMBL· GenBank· DDBJ
Genomic DNA

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