A0AA36KBK8 · A0AA36KBK8_ACINO
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids242 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- UMP + ATP = UDP + ADP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 15-18 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KLSG | ||||||
Binding site | 57 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 58 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 62 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 78 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 139-146 | UMP (UniProtKB | ChEBI) | ||||
Sequence: TGNPFFTT | ||||||
Binding site | 166 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 172 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 175 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | phosphorylation | |
Biological Process | UDP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex
Accessions
- Primary accessionA0AA36KBK8
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 11-220 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: RILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNLYRGSQLQKDGLVGRVTGDQMGMLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSSRDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEANLILKATKVDGVYNKDPSKYEDAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFD |
Sequence similarities
Belongs to the UMP kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length242
- Mass (Da)26,136
- Last updated2024-01-24 v1
- ChecksumAA3DBB39BB67FD4B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CBSD020000047 EMBL· GenBank· DDBJ | CDG75170.1 EMBL· GenBank· DDBJ | Genomic DNA |