A0AA36HYU2 · A0AA36HYU2_9DINO

  • Protein
    Endonuclease/exonuclease/phosphatase domain-containing protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site, site.

132850100150200250300
Type
IDPosition(s)Description
Binding site47Mg2+ 1 (UniProtKB | ChEBI)
Binding site79Mg2+ 1 (UniProtKB | ChEBI)
Active site168
Active site212Proton donor/acceptor
Binding site212Mg2+ 2 (UniProtKB | ChEBI)
Binding site214Mg2+ 1 (UniProtKB | ChEBI)
Site214Transition state stabilizer
Site287Important for catalytic activity
Binding site316Mg2+ 1 (UniProtKB | ChEBI)
Active site317Proton acceptor
Binding site317Mg2+ 1 (UniProtKB | ChEBI)
Site317Interaction with DNA substrate

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA binding
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionendonuclease activity
Molecular Functionmetal ion binding
Molecular Functionphosphoric diester hydrolase activity
Biological Processbase-excision repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Endonuclease/exonuclease/phosphatase domain-containing protein

Gene names

    • ORF names
      EVOR1521_LOCUS6557

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Effrenium

Accessions

  • Primary accession
    A0AA36HYU2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_504121137621-328Endonuclease/exonuclease/phosphatase domain-containing protein

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain44-317Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    328
  • Mass (Da)
    36,585
  • Last updated
    2024-01-24 v1
  • MD5 Checksum
    9F9B9827F2E3031E9442ADDF5E3FA221
MKLRRALVLLPALMIASGMAAWKRYIACSLTSSMLNRPEQLKILSWNVASLRSMLKRESGDELRKLVEREQPDITFLQEHKLQDIHVPKVAPELLRIFDLACPGESHRATWAVSKARKGYSGVCAIYRQSVGGGVLRAAVGEVDEVDAAEGRSVRLDLQCGLIVVGIYSPNSGQRLARLDYRVSVWDSKLRSYLKKLDTEAGCEGGLLLCGDLNVAHEDIDFWNPTSARTRRQAGTTPQERQSFTAWLAELDMIDMFRFKNPETEGVFTYWNRRTNGRPANKGMRLDYFLGSRRLCSSSQVAVSDCQVLGAFGGSDHCPISCVVEVAK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAUJNA010000495
EMBL· GenBank· DDBJ
CAJ1377862.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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