A0AA36HYU2 · A0AA36HYU2_9DINO
- ProteinEndonuclease/exonuclease/phosphatase domain-containing protein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids328 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Probably binds two magnesium or manganese ions per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 47 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 79 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 168 | ||||
Active site | 212 | Proton donor/acceptor | |||
Binding site | 212 | Mg2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 214 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 214 | Transition state stabilizer | |||
Site | 287 | Important for catalytic activity | |||
Binding site | 316 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 317 | Proton acceptor | |||
Binding site | 317 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Site | 317 | Interaction with DNA substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | |
Molecular Function | endonuclease activity | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoric diester hydrolase activity | |
Biological Process | base-excision repair |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameEndonuclease/exonuclease/phosphatase domain-containing protein
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Effrenium
Accessions
- Primary accessionA0AA36HYU2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-20 | ||||
Chain | PRO_5041211376 | 21-328 | Endonuclease/exonuclease/phosphatase domain-containing protein | ||
Structure
Sequence
- Sequence statusComplete
- Length328
- Mass (Da)36,585
- Last updated2024-01-24 v1
- MD5 Checksum9F9B9827F2E3031E9442ADDF5E3FA221
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAUJNA010000495 EMBL· GenBank· DDBJ | CAJ1377862.1 EMBL· GenBank· DDBJ | Genomic DNA |