A0AA36HCZ9 · A0AA36HCZ9_CYLNA
- Proteinphospholipase A2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1220 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+This reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 928 | Nucleophile | |||
Active site | 1055 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | mitochondrion | |
Molecular Function | calcium-independent phospholipase A2 activity | |
Biological Process | lipid catabolic process | |
Biological Process | positive regulation of ceramide biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namephospholipase A2
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Strongyloidea > Strongylidae > Cylicocyclus
Accessions
- Primary accessionA0AA36HCZ9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 103-124 | Helical | |||
Transmembrane | 271-296 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, repeat, domain, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 162-265 | Disordered | |||
Compositional bias | 164-189 | Pro residues | |||
Compositional bias | 194-208 | Basic and acidic residues | |||
Compositional bias | 234-265 | Polar residues | |||
Region | 340-367 | Disordered | |||
Repeat | 563-595 | ANK | |||
Repeat | 631-663 | ANK | |||
Repeat | 732-764 | ANK | |||
Repeat | 765-797 | ANK | |||
Domain | 890-1068 | PNPLA | |||
Motif | 894-899 | GXGXXG | |||
Motif | 926-930 | GXSXG | |||
Motif | 1055-1057 | DGA/G | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,220
- Mass (Da)135,653
- Last updated2024-01-24 v1
- MD5 Checksum60C62EA3E21FA191D523C6EFBE861A36
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 164-189 | Pro residues | |||
Compositional bias | 194-208 | Basic and acidic residues | |||
Compositional bias | 234-265 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CATQJL010000316 EMBL· GenBank· DDBJ | CAJ0607980.1 EMBL· GenBank· DDBJ | Genomic DNA |