A0AA35W6A0 · A0AA35W6A0_GEOBA
- ProteinLysosomal dipeptide transporter MFSD1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids555 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
Catalytic activity
- L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)
- L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)
- L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)
- L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)
- L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)
- L-arginyl-glycine(out) = L-arginyl-glycine(in)
- L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)
- L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)
- L-histidyl-glycine(out) = L-histidyl-glycine(in)
- L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)
- L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)
- L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)
- L-lysyl-glycine(out) = L-lysyl-glycine(in)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | lysosomal membrane | |
Molecular Function | transmembrane transporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameLysosomal dipeptide transporter MFSD1
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Porifera > Demospongiae > Heteroscleromorpha > Tetractinellida > Astrophorina > Geodiidae > Geodia
Accessions
- Primary accessionA0AA35W6A0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Lysosome membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 59-80 | Helical | ||||
Sequence: WLHRFLLLFLMCMLSFGSYYVY | ||||||
Transmembrane | 101-123 | Helical | ||||
Sequence: YALLYSLYSWPNVILSVFGGYLI | ||||||
Transmembrane | 129-153 | Helical | ||||
Sequence: VRLGTLIFSGFVCLGQLVFALGAFV | ||||||
Transmembrane | 231-254 | Helical | ||||
Sequence: GTVLFIGLGFCLLSLLAGVVLGLF | ||||||
Transmembrane | 284-310 | Helical | ||||
Sequence: LWIIFLVCVCYYVTVFPFIGLAVIFLM | ||||||
Transmembrane | 322-342 | Helical | ||||
Sequence: IINSLVYIISAAASPFLGILV | ||||||
Transmembrane | 349-369 | Helical | ||||
Sequence: LFWLNLGILFTLGAHAMLAFL | ||||||
Transmembrane | 375-398 | Helical | ||||
Sequence: LPYFAMALMGVAYSLLACALWPLV | ||||||
Transmembrane | 410-433 | Helical | ||||
Sequence: AYGIMQAIQNLGLAIVPIVAGYIV | ||||||
Transmembrane | 439-462 | Helical | ||||
Sequence: LILEVFFVAMLCIALISGVFLYIL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-30 | Basic and acidic residues | ||||
Sequence: MSEEKEALMPARDSASLGESDEEAETRRAA | ||||||
Region | 1-33 | Disordered | ||||
Sequence: MSEEKEALMPARDSASLGESDEEAETRRAAAAV | ||||||
Domain | 62-467 | Major facilitator superfamily (MFS) profile | ||||
Sequence: RFLLLFLMCMLSFGSYYVYDNPASLEKTIINVMGVSVTQYALLYSLYSWPNVILSVFGGYLIDRVLGVRLGTLIFSGFVCLGQLVFALGAFVDKYWLMLVGRFVFGLGGENLAVAQNNYAVLWFKGKELNMVFGILLSVSRIGSTVNMNINQKLYSHYFENVNPNFVRLGTVLFIGLGFCLLSLLAGVVLGLFDKRAEIITKRKSGDGERISLKDIKDFPLRLWIIFLVCVCYYVTVFPFIGLAVIFLMEKYGYEAKQANIINSLVYIISAAASPFLGILVDRTGLNLFWLNLGILFTLGAHAMLAFLGTATWLPYFAMALMGVAYSLLACALWPLVSFIVPEHQLGTAYGIMQAIQNLGLAIVPIVAGYIVDNNGYLILEVFFVAMLCIALISGVFLYILDSGAG | ||||||
Compositional bias | 482-502 | Basic and acidic residues | ||||
Sequence: KEKKAREEMESEKKKAGEAMK | ||||||
Region | 482-506 | Disordered | ||||
Sequence: KEKKAREEMESEKKKAGEAMKTRGG |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length555
- Mass (Da)61,585
- Last updated2024-01-24 v1
- Checksum011638B0E5503F70
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0AA35W464 | A0AA35W464_GEOBA | GBAR_LOCUS2086 | 742 | ||
A0AA35W2C0 | A0AA35W2C0_GEOBA | GBAR_LOCUS2086 | 341 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-30 | Basic and acidic residues | ||||
Sequence: MSEEKEALMPARDSASLGESDEEAETRRAA | ||||||
Compositional bias | 482-502 | Basic and acidic residues | ||||
Sequence: KEKKAREEMESEKKKAGEAMK |
Keywords
- Technical term