A0AA35RP73 · A0AA35RP73_GEOBA
- ProteinSerine/threonine-protein kinase receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids559 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-threonyl-[receptor-protein] + ATP = O-phospho-L-threonyl-[receptor-protein] + ADP + H+
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 283 | ATP (UniProtKB | ChEBI) | |||
Active site | 384 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | activin receptor complex | |
Molecular Function | activin binding | |
Molecular Function | activin receptor activity, type I | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to growth factor stimulus | |
Biological Process | nervous system development | |
Biological Process | protein phosphorylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase receptor
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Porifera > Demospongiae > Heteroscleromorpha > Tetractinellida > Astrophorina > Geodiidae > Geodia
Accessions
- Primary accessionA0AA35RP73
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 170-199 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 11↔17 | ||||
Disulfide bond | 91↔96 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 116-167 | Disordered | |||
Domain | 225-255 | GS | |||
Domain | 256-550 | Protein kinase | |||
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length559
- Mass (Da)61,381
- Last updated2024-01-24 v1
- Checksum038988DCB36E1C19
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CASHTH010001387 EMBL· GenBank· DDBJ | CAI8014689.1 EMBL· GenBank· DDBJ | Genomic DNA |