A0A9X9N6J4 · A0A9X9N6J4_NEISU

  • Protein
    Fluoride-specific ion channel FluC
  • Gene
    fluC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

1119102030405060708090100110
TypeIDPosition(s)Description
Binding site69Na+ (UniProtKB | ChEBI); structural
Binding site72Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • ORF names
      KCG53_08235

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CG0073
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria

Accessions

  • Primary accession
    A0A9X9N6J4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-26Helical
Transmembrane32-54Helical
Transmembrane61-84Helical
Transmembrane90-112Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    119
  • Mass (Da)
    12,798
  • Last updated
    2023-11-08 v1
  • MD5 Checksum
    FDCEF0289C1B1F9D303F987FE836DD34
MFAYIFPIVCGAAVGAVLRWLFGLVLVSSTPFSIGTLAANWLGALLIGVLAELLTDPQWRLLWITGFLGSLTTFSGFSVEMVGLMQAQRWGMAAMATCLHVFGSFGLTALGIKLAQIWK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP073118
EMBL· GenBank· DDBJ
UTG75231.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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