A0A9X7UHI1 · A0A9X7UHI1_SPHYA
- ProteinGTP cyclohydrolase 1
- GenefolE
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids200 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H+
Pathway
Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 90 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 93 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 161 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTP cyclohydrolase I activity | |
Molecular Function | zinc ion binding | |
Biological Process | one-carbon metabolic process | |
Biological Process | tetrahydrobiopterin biosynthetic process | |
Biological Process | tetrahydrofolate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGTP cyclohydrolase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A9X7UHI1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homopolymer.
Toroid-shaped homodecamer, composed of two pentamers of five dimers.
Structure
Sequence
- Sequence statusComplete
- Length200
- Mass (Da)22,436
- Last updated2023-11-08 v1
- Checksum79DE9A52AD697D2D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP060122 EMBL· GenBank· DDBJ | QNG48934.1 EMBL· GenBank· DDBJ | Genomic DNA |