A0A9X7UAM0 · A0A9X7UAM0_SPHYA
- ProteinBifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada
- Geneada
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids357 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 46 | Nucleophile; methyl group acceptor from methylphosphotriester | ||||
Sequence: C | ||||||
Binding site | 46 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 50 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 77 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 80 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Active site | 323 | Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | methylated-DNA-[protein]-cysteine S-methyltransferase activity | |
Molecular Function | sequence-specific DNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | DNA repair | |
Biological Process | methylation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A9X7UAM0
Proteomes
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length357
- Mass (Da)38,340
- Last updated2023-11-08 v1
- Checksum58BA005367926154