A0A9X4XG53 · A0A9X4XG53_9FIRM
- ProteinNADPH-dependent 7-cyano-7-deazaguanine reductase
- GenequeF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids165 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
Catalytic activity
- 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH
Pathway
tRNA modification; tRNA-queuosine biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 56 | Thioimide intermediate | ||||
Sequence: C | ||||||
Active site | 63 | Proton donor | ||||
Sequence: D | ||||||
Binding site | 78-80 | substrate | ||||
Sequence: VES | ||||||
Binding site | 97-98 | substrate | ||||
Sequence: HE |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | preQ1 synthase activity | |
Biological Process | queuosine biosynthetic process | |
Biological Process | tRNA modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADPH-dependent 7-cyano-7-deazaguanine reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Erysipelotrichia > Erysipelotrichales > Turicibacteraceae > Turicibacter
Accessions
- Primary accessionA0A9X4XG53
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length165
- Mass (Da)19,344
- Last updated2023-11-08 v1
- ChecksumAB375C337CD05189
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WMQE01000013 EMBL· GenBank· DDBJ | MTK21205.1 EMBL· GenBank· DDBJ | Genomic DNA |