A0A9X2ILC5 · A0A9X2ILC5_9HYPH
- ProteinSiroheme synthase CysG
- GenecysG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids496 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- precorrin-2 + NAD+ = sirohydrochlorin + NADH + 2 H+
Pathway
Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.
Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 273 | Proton acceptor | |||
Active site | 295 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | NAD binding | |
Molecular Function | precorrin-2 dehydrogenase activity | |
Molecular Function | sirohydrochlorin ferrochelatase activity | |
Molecular Function | uroporphyrin-III C-methyltransferase activity | |
Biological Process | cobalamin biosynthetic process | |
Biological Process | methylation | |
Biological Process | siroheme biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Ciceribacter
Accessions
- Primary accessionA0A9X2ILC5
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 150-170 | Siroheme synthase central | |||
Domain | 177-214 | Sirohaem synthase dimerisation | |||
Domain | 243-454 | Tetrapyrrole methylase | |||
Sequence similarities
Belongs to the precorrin methyltransferase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length496
- Mass (Da)53,207
- Last updated2023-11-08 v1
- MD5 ChecksumE3FE8931DEF284F37D991DC369C745ED
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAMQAX010000023 EMBL· GenBank· DDBJ | MCM2398205.1 EMBL· GenBank· DDBJ | Genomic DNA |