A0A9X2ILC5 · A0A9X2ILC5_9HYPH

  • Protein
    Siroheme synthase CysG
  • Gene
    cysG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.
Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site273Proton acceptor
Active site295Proton donor

GO annotations

AspectTerm
Molecular FunctionNAD binding
Molecular Functionprecorrin-2 dehydrogenase activity
Molecular Functionsirohydrochlorin ferrochelatase activity
Molecular Functionuroporphyrin-III C-methyltransferase activity
Biological Processcobalamin biosynthetic process
Biological Processmethylation
Biological Processsiroheme biosynthetic process

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Siroheme synthase CysG
      (EC:1.3.1.76
      , EC:2.1.1.107
      , EC:4.99.1.4
      )

Gene names

    • Name
      cysG
    • ORF names
      NBH19_19215

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • S95
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Ciceribacter

Accessions

  • Primary accession
    A0A9X2ILC5

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain150-170Siroheme synthase central
Domain177-214Sirohaem synthase dimerisation
Domain243-454Tetrapyrrole methylase

Sequence similarities

Belongs to the precorrin methyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    496
  • Mass (Da)
    53,207
  • Last updated
    2023-11-08 v1
  • MD5 Checksum
    E3FE8931DEF284F37D991DC369C745ED
MPAMPLRLSEPKPTTTARVAPLAKLPVFWSLAGKQTIVAGGSDGAAWKAELLAACGAEVHVYCPNEELGEAMKALIDETAVRSIIHHPHAWHPGIFTGKALALADCETQEEAQAFHDAARAAGVPVNVIDKPDFCQFQFGSIVNRSPVVVAISTDGAAPILAQAIRRRIETLLPPALKSWAELAQALRERANTLLTTPQSRRNFWERFVDRAFAGNRPPEESDGQSLLADAERLAVDQTHGHVTLVGAGPGDAELLTLKAVRALQSADAILFDDLVSAEVLELARREAKRMLVGKRGGRESCRQEDINDTMLALAKAGKRVVRLKSGDPMIFGRAGEEIAFLERHGISCDVVPGITAASAMAASLGVSLTHRDHAQAVRFVTGHARSGDLPADLDWRNLADPKTTTVFYMGGRTAGKIRSRLLDAGMAPDLPVVVASSVTRSSQRSWAGCLNDLERGISEIGYENPVLIGIGPVFQACRRNTDRSDLPAPAHAGRV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAMQAX010000023
EMBL· GenBank· DDBJ
MCM2398205.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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