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A0A9X0PWZ0 · A0A9X0PWZ0_9ESCH

  • Protein
    Bifunctional protein PutA
  • Gene
    putA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Oxidizes proline to glutamate for use as a carbon and nitrogen source.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.
Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site883
Active site917

GO annotations

AspectTerm
Cellular Componentcytoplasmic side of plasma membrane
Molecular Function1-pyrroline-5-carboxylate dehydrogenase activity
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionproline dehydrogenase activity
Molecular Functionsequence-specific DNA binding
Biological Processproline biosynthetic process
Biological Processproline catabolic process to glutamate

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional protein PutA

Including 2 domains:

  • Recommended name
    Proline dehydrogenase
  • EC number
  • Alternative names
    • Proline oxidase
  • Recommended name
    Delta-1-pyrroline-5-carboxylate dehydrogenase
  • EC number
  • Short names
    P5C dehydrogenase
  • Alternative names
    • L-glutamate gamma-semialdehyde dehydrogenase

Gene names

    • Name
      putA
    • ORF names
      HEN21_009480

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 93.1518
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A9X0PWZ0

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-43PutA RHH
Domain89-136Proline utilization A proline dehydrogenase N-terminal
Domain148-259Proline dehydrogenase PutA
Domain268-569Proline dehydrogenase
Domain659-1103Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.
In the C-terminal section; belongs to the aldehyde dehydrogenase family.
In the N-terminal section; belongs to the proline dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,320
  • Mass (Da)
    143,916
  • Last updated
    2023-11-08 v1
  • MD5 Checksum
    4F27BCF7FD2D101E5E118A216D0CF5CE
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPIAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPMVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKMAQQEGQTGLPHPKIPLPRDLYGQGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALENAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGISILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALIQPLNALREWAANRTELQALCAQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSRVLWTDDTLHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABWMT020000010
EMBL· GenBank· DDBJ
MBB2318514.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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