A0A9W9AUA7 · A0A9W9AUA7_9AGAR

  • Protein
    Carbamoyl phosphate synthase arginine-specific small chain
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site338Nucleophile
Active site422
Active site424

GO annotations

AspectTerm
Cellular Componentcarbamoyl-phosphate synthase complex
Molecular Functionamino acid binding
Molecular Functionaspartate carbamoyltransferase activity
Molecular FunctionATP binding
Molecular Functioncarbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Molecular Functionhydrolase activity
Molecular Functionmetal ion binding
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Processarginine biosynthetic process
Biological Processglutamine metabolic process
Biological Processpyrimidine nucleotide biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Carbamoyl phosphate synthase arginine-specific small chain
  • EC number
  • Alternative names
    • Arginine-specific carbamoyl phosphate synthetase, glutamine chain

Gene names

    • ORF names
      J3R30DRAFT_124567

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • JLM2183
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Marasmiineae > Omphalotaceae > Lentinula

Accessions

  • Primary accession
    A0A9W9AUA7

Proteomes

Subcellular Location

Interaction

Subunit

Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-22Disordered
Region196-216Disordered
Compositional bias202-216Polar residues
Domain598-790ATP-grasp
Domain1133-1324ATP-grasp
Domain1389-1570MGS-like

Sequence similarities

Belongs to the CarA family.
In the 2nd section; belongs to the CarB family.
In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.
In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
In the N-terminal section; belongs to the CarA family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,236
  • Mass (Da)
    245,199
  • Last updated
    2023-11-08 v1
  • Checksum
    D885D56E7B17A140
MVLSTSSDAPARPSLTRATSNFSQKIPTPAASAAITSSDSDVDAVLEFSDGSAYRGISFGAEGKSIAGECVFQTGMVGYPESLTDPSYKGQILVFTYPLIGNYGVPERPSHPLDDIPLEFESSCMHIAALVVGYYSKDFSHFLAKSSLATCLKENGVPAIYGVDTRVLTKKIREKGSMLGKLLARNPEAHVGRKLTINPPLSAAPSRASSPNSRSSWRDDYLDIPFSDPNQMNLVAAVSITEPRFYKALGTPLLHPSGRPLRVLVLDVGMKYNQIRCFINRGVELKVLPWDYDFLSEPEPYDGLFVSNGPGDPTMVKYTIARLAKAMERADRPIFGICLGHQLMALAAGAHTSKMKYGNRGHNIPCTDALSGRCYITSQNHGFQVDTDSLPSGWKELFRNANDNSNEGIYCVDKPFFSVQFHPESTPGPRDTEFLFDVFIKNVLDCATTNSLVPISMPGGKKEDNDKRIPRAKVSKVIILGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTIMVNPNIATIATSKGLADKVYFLPVTPEFVRKIIKYEKPDGIYVTFGGQTALNVGIKLKDEFAALGVQVLGTPIDTIITTEDRQLFGSAMEEIGEKCAKSFTATNSDEAITAAHAIGFPVIVRAAYALGGLGSGFAQNVDQLKALCSKAFATSPQVLVEKSMKGWKEIEYEVVRDCRDNCITVCNMENFDPLGIHTGDSIVIAPSQTLSDSDYNMLRTTAINVIRHLGVVGECNIQYALNPESQQYCIIEVNARLSRSSALASKATGYPLAFIAAKLGLGIPLNEIKNSVTKVTSACFEPSLDYVVVKIPRWDLKKFNRVSRLLSSSMKSVGEVMSIGRTFEETFQKAIRAIDDQFSGFAKNEYVEDIDEELINPTDKRIFAISTAFHRGYSVDKIWQMTNIDKWFLTKLQYIFRMEEHLMGLNINTISEEDLRRSKQLGFCDRQLAGCLGSTELAVRRLRQELGIAPFVKQIDTVAAEFPAFTNYLYTTYNAIENDITFEERGVMVLGSGVYRIGSSVEFDWCAVRAIRTLRDQGLPTVMVNYNPETVSTDYDEADRLYFENISLETILDIYDAERARGVILSMGGQTPNNIALPLYRQNVKIYGTSPEMIDTAENRFKFSRLLDEIGVDQPLWKELTSFEEAEVFCEKVGYPVLVRPSYVLSGAAMNVVSTGDDLANYLTQAAAVSRDHPVVITKYIEQAKEIEMDAVAKDGKMIMHYISEHVENAGVHSGDATLIHPPQDLDPQTVRQIEEATAKIGNALNVTGPYNIQFIAKNNEIKVIECNLRAARSFPFVSKVTGIDAIEMATKVMLGIPVEPYPDAGMPSDYVGVKVPQFSFSRLSGADPVLGVEMASTGEVACFGKDKYEAYLKALISTGIVPPKKNILFSIGSYREKLELLPSVQRLSAAGYNIFATSGTADFLTEHNVSCKYLETLGDDSRDAQKSEYSLTQHLANNLIDMYINLPSKNHYRRPASYTSKGYHTRRMAVDFAIPLITNVKNAKMLAEALVRKLPLNVSSVDSKSSHRTHTFPGLINVAAFVPGLATVNNQDFIEATRASISAGFTTSIVIPQAQDNGIVDRATLEVAKANVLGSAYCNFALSLSASADNVHIFDEELKADVKALFIPFRIANKPVPLSAVAAHFSSWPTEKPIITDAKGSDLASLLLLASLHSRSIHVTDVQNIDDVLLISLSKAKNLKVTCDVSVYSLFFTRDQFPAASFLPSPEDQKALWKKLDLIDAFSVGSSPYKLSLEIHEAGSPASGMEEALPLLLTAVTEGRLSLQDITTRLHDNPVQIFGLPEQTQTHVEVVLGRQAPFAARPSCWSPLGQTLVSGSIHRVIVHGQTSFLDGDLSKIPMGKDISSATISHGSSAVVPASPALKPFEHLLSTTAIAPSQPGGPLVYGPLTHSQQHFTSIQPHPSFYRRHILSVKQFTHQDMYDLFSLAHEMRLQVERNGTLDILKGKVLCTAFYEPSTRTSSSFDAAMKRCGGQVVQITADSSSVAKGESLPDTIRTLGCYGDAIVIRHPDVGSAQTAAKFSSVPIINAGDGIGEHPTQALLDVYTIRSELGTVNGRTITLLGDLKNGRTVHSLVTLLCLYSIRLNFVSPPSLSMPSSVVSVARKAGVSVHQCESLDEVLADTDVLYVTRVQKERFESEVEWQQVKDAYRVDHAVLSRAKEEMIVMHPLPRVNEIDPEVDFDSRRAAYFRQMRYGLFIRMALLASVMG

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias202-216Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAOTPV010000001
EMBL· GenBank· DDBJ
KAJ4490714.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help