A0A9W8H4N3 · A0A9W8H4N3_9FUNG
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids605 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 147 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 417 | Nucleophile | ||||
Sequence: T | ||||||
Binding site | 435-437 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: TIN | ||||||
Binding site | 459 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 487-488 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: SS | ||||||
Binding site | 509 | L-glutamate (UniProtKB | ChEBI) | ||||
Sequence: G |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Zoopagomycota > Kickxellomycotina > Kickxellomycetes > Kickxellales > Kickxellaceae > Coemansia
Accessions
- Primary accessionA0A9W8H4N3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 40-61 | Helical | ||||
Sequence: VLRACAVALLVALFGGGLVAVA |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length605
- Mass (Da)63,465
- Last updated2023-11-08 v1
- Checksum6CA7C76E8D91BB29
Keywords
- Technical term