A0A9W5T839 · A0A9W5T839_BABOV
- ProteinElongation factor G, mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1121 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
Pathway
Protein biosynthesis; polypeptide chain elongation.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 431-438 | GTP (UniProtKB | ChEBI) | |||
Binding site | 508-512 | GTP (UniProtKB | ChEBI) | |||
Binding site | 562-565 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | translation elongation factor activity | |
Biological Process | mitochondrial translational elongation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameElongation factor G, mitochondrial
- Short namesEF-Gmt
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Sar > Alveolata > Apicomplexa > Aconoidasida > Piroplasmida > Babesiidae > Babesia
Accessions
- Primary accessionA0A9W5T839
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 50-99 | Disordered | |||
Domain | 422-708 | Tr-type G | |||
Sequence similarities
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,121
- Mass (Da)125,703
- Last updated2023-11-08 v1
- Checksum5AA32BC37D68132E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BLIY01000001 EMBL· GenBank· DDBJ | GFE52711.1 EMBL· GenBank· DDBJ | Genomic DNA |